This paper presents the 12th update of the human obesity gene map, which incorporates
published results up to the end of October 2005. Evidence from single‐gene mutation …

Adipose tissue is an active metabolic tissue that secretes multiple metabolically important
proteins, known as adipokines. Adiponectin is an important adipokine because of its …

Recent evidence points to molecules secreted by the adipose tissue, or adipokines, as
possible links between increased adipose mass and metabolic abnormalities. Among these …

Several pathophysiological explanations for the metabolic syndrome have been proposed
involving insulin resistance, chronic inflammation and ectopic fat accumulation following …

Type 2 diabetes mellitus is a complex metabolic disease that is caused by insulin resistance
and β-cell dysfunction. Furthermore, type 2 diabetes has an evident genetic component and …

The increasing prevalence of obesity and metabolic syndrome/insulin resistance has
attracted considerable interest due to their identification as risk factors for cardiovascular …

Objective Hypoadiponectinemia contributes to the development of obesity and related
disorders such as diabetes, hyperlipidemia, and cardiovascular diseases. In this study we …

Objective We explored potential associations of two single nucleotide polymorphisms
(SNPs) in the adiponectin gene (ADIPOQ;+ 45T> G, rs2241766 and+ 276G> T, rs1501299) …

Diabetes mellitus is a combined metabolic disorder which includes hyperglycemia,
dyslipidemia, stroke and several other complications. Various groups all over the world are …

Obesity rates are rapidly increasing worldwide and facilitate the development of many
related disease states, such as cardiovascular disease, the metabolic syndrome, type 2 …