Metabolomics of infectious diseases in the era of personalized medicine
M Rahman, HE Schellhorn - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Infectious diseases continue to be a major cause of morbidity and mortality worldwide.
Diseases cause perturbation of the host's immune system provoking a response that …
Diseases cause perturbation of the host's immune system provoking a response that …
An update on drug-drug interactions in older adults living with human immunodeficiency virus (HIV)
RY Linfield, NN Nguyen, OH Laprade… - Expert Review of …, 2024 - Taylor & Francis
Introduction People with HIV are living longer due to advances in antiretroviral therapy. With
improved life expectancy comes an increased lifetime risk of comorbid conditions–such as …
improved life expectancy comes an increased lifetime risk of comorbid conditions–such as …
Cocaine regulates antiretroviral therapy CNS access through pregnane-x receptor-mediated drug transporter and metabolizing enzyme modulation at the blood brain …
R Colón Ortiz, S Knerler, LB Fridman… - Fluids and Barriers of …, 2024 - Springer
Background Appropriate interactions between antiretroviral therapies (ART) and drug
transporters and metabolizing enzymes at the blood brain barrier (BBB) are critical to ensure …
transporters and metabolizing enzymes at the blood brain barrier (BBB) are critical to ensure …
Pharmacokinetic drug-drug interactions involving antiretroviral agents: an update
X Yu, L Zhao, Z Yuan, Y Li - Current Drug Metabolism, 2023 - ingentaconnect.com
Antiretroviral therapy is the recognized treatment for human immunodeficiency virus (HIV)
infection involving several antiviral agents. Even though highly active antiretroviral therapy …
infection involving several antiviral agents. Even though highly active antiretroviral therapy …
The Impact of Certain Pharmacogenetic Differences on the Metabolism of Antiretroviral Drugs Used in A Black South African Population
R Reay, M Viljoen, M Rheeders - Current Drug Metabolism, 2023 - ingentaconnect.com
Background: Genetic polymorphism of drug-metabolising enzymes and transporters may
influence the effect and toxicity of antiretroviral drugs. Objectives: To determine and compare …
influence the effect and toxicity of antiretroviral drugs. Objectives: To determine and compare …
[HTML][HTML] Cocaine Regulates Antiretroviral Therapy CNS Access Through Pregnane-X Receptor-Mediated Drug Transporter and Metabolizing Enzyme Modulation at …
LB Fridman, S Knerler, AS Price, RC Ortiz, A Mercado… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Background Appropriate interactions between antiretroviral therapies (ART) and drug
transporters and metabolizing enzymes at the blood brain barrier (BBB) are critical to ensure …
transporters and metabolizing enzymes at the blood brain barrier (BBB) are critical to ensure …
[HTML][HTML] Pharmacogenetics of HIV therapy: State of the art in Latin American countries
CA Velozo, FRM Lamarão… - … and molecular biology, 2022 - SciELO Brasil
The use of combined antiretroviral therapy (cART) has resulted in a remarkable reduction in
morbidity and mortality of people living with HIV worldwide. Nevertheless, interindividual …
morbidity and mortality of people living with HIV worldwide. Nevertheless, interindividual …
[PDF][PDF] Impact of interindividual differences on muscle-type creatine kinase: implications for tenofovir-based PrEP
EP Mosher - 2022 - jscholarship.library.jhu.edu
Tenofovir (TFV) is a key component to FDA-approved regimens for HIV preexposure
prophylaxis (PrEP). TFV is a nucleotide analog reverse transcriptase inhibitor prodrug that …
prophylaxis (PrEP). TFV is a nucleotide analog reverse transcriptase inhibitor prodrug that …