Thrombolysis and myocardial salvage. Results of clinical trials and the animal paradigm--paradoxic or predictable?

BJ Gersh, JL Anderson - Circulation, 1993 - Am Heart Assoc
T he era of acute reperfusion has witnessed a dramatic change in the management of acute
myocardial infarction in an expanding group of patients who are considered eligible for this …

Mortality and prehospital thrombolysis for acute myocardial infarction: a meta-analysis

LJ Morrison, PR Verbeek, AC McDonald, BV Sawadsky… - Jama, 2000 - jamanetwork.com
ContextEarly administration of thrombolysis for acute myocardial infarction (AMI) may
improve survival if safely and appropriately delivered. No systematic reviews that have …

TIMI perfusion grade 3 but not grade 2 results in improved outcome after thrombolysis for myocardial infarction. Ventriculographic, enzymatic, and electrocardiographic …

JL Anderson, LA Karagounis, LC Becker… - Circulation, 1993 - Am Heart Assoc
BACKGROUND Coronary patency has been used as a measure of thrombolysis success
after acute myocardial infarction. The Thrombolysis in Myocardial Infarction (TIMI) Study …

Patient delay in seeking care for heart attack symptoms: findings from focus groups conducted in five US regions

JR Finnegan Jr, H Meischke, JG Zapka, L Leviton… - Preventive …, 2000 - Elsevier
Background. Patient delay in seeking health care for heart attack symptoms is a continuuing
problem in the United States. Methods. Investigators conducted focus groups (N= 34; 207 …

Aortic counterpulsation may improve late patency of the occluded coronary artery in patients with early failure of thrombolytic therapy

T Kono, H Morita, T Nishina, M Fujita, H Onaka… - Journal of the American …, 1996 - jacc.org
Objectives. Using a prospective, randomized design, we tested our hypothesis that the
augmentation of diastolic pressure by intraaortic balloon counterpulsation (IABP) would …

Formative research methods to understand patient and provider responses to heart attack symptoms

LC Leviton, JR Finnegan Jr, JG Zapka… - Evaluation and Program …, 1999 - Elsevier
Formative research is often required for program planning, and for reducing uncertainty
about generalizability of program effects. This article describes and justifies methods of …