Tuberculosis: progress and advances in development of new drugs, treatment regimens, and host-directed therapies
Tuberculosis remains the world's leading cause of death from an infectious disease,
responsible for an estimated 1 674 000 deaths annually. WHO estimated 600 000 cases of …
responsible for an estimated 1 674 000 deaths annually. WHO estimated 600 000 cases of …
Vaccines against antimicrobial resistance
In the last century, life expectancy has increased considerably, thanks to the introduction of
antibiotics, hygiene and vaccines that have contributed to the cure and prevention of many …
antibiotics, hygiene and vaccines that have contributed to the cure and prevention of many …
Recent advances in the treatment of tuberculosis
Background Tuberculosis (TB) is a global health challenge and one of the leading causes of
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …
death worldwide. In the last decade, the TB treatment landscape has dramatically changed …
Principles for constructing a tuberculosis treatment regimen: the role and definition of core and companion drugs
A Van Deun, T Decroo, A Piubello… - … of Tuberculosis and …, 2018 - ingentaconnect.com
Current World Health Organization guidelines for the formulation of treatment regimens for
multidrug-resistant tuberculosis (MDR-TB) pay too little attention to the microbiological …
multidrug-resistant tuberculosis (MDR-TB) pay too little attention to the microbiological …
Mannose-Functionalized Isoniazid-Loaded Nanostructured Lipid Carriers for Pulmonary Delivery: In Vitro Prospects and In Vivo Therapeutic Efficacy Assessment
Resistance to isoniazid (INH) is common and increases the possibility of acquiring multidrug-
resistant tuberculosis. For this study, isoniazid-loaded nanostructured lipid carriers (INH …
resistant tuberculosis. For this study, isoniazid-loaded nanostructured lipid carriers (INH …
[HTML][HTML] New and repurposed drugs to treat multidrug-and extensively drug-resistant tuberculosis
Multidrug-resistant and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB,
respectively) continue to represent a challenge for clinicians and public health authorities …
respectively) continue to represent a challenge for clinicians and public health authorities …
Novel approaches for the treatment of pulmonary tuberculosis
Tuberculosis (TB) is a contagious airborne disease caused by Mycobacterium tuberculosis,
which primarily affects human lungs. The progression of drug-susceptible TB to drug …
which primarily affects human lungs. The progression of drug-susceptible TB to drug …
[HTML][HTML] Treatment of isoniazid-resistant pulmonary tuberculosis
BW Jhun, WJ Koh - Tuberculosis and Respiratory Diseases, 2020 - synapse.koreamed.org
Tuberculosis (TB) remains a threat to public health and is the leading cause of death
globally. Isoniazid (INH) is an important first-line agent for the treatment of TB considering its …
globally. Isoniazid (INH) is an important first-line agent for the treatment of TB considering its …
Tuberculous meningitis in children and adults: new insights for an ancient foe
A Mezochow, K Thakur, C Vinnard - Current neurology and neuroscience …, 2017 - Springer
Abstract Purpose of Review Tuberculous meningitis is the most devastating manifestation of
infection with Mycobacterium tuberculosis and represents a medical emergency …
infection with Mycobacterium tuberculosis and represents a medical emergency …
Isoniazid linked to sulfonate esters via hydrazone functionality: design, synthesis, and evaluation of antitubercular activity
E Koçak Aslan, Mİ Han, VS Krishna, R Tamhaev… - Pharmaceuticals, 2022 - mdpi.com
Isoniazid (INH) is one of the key molecules employed in the treatment of tuberculosis (TB),
the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug …
the most deadly infectious disease worldwide. However, the efficacy of this cornerstone drug …