Role of dipeptidyl peptidase-4 (DPP4) on COVID-19 physiopathology

A Sebastián-Martín, BG Sánchez, JM Mora-Rodríguez… - Biomedicines, 2022 - mdpi.com
DPP4/CD26 is a single-pass transmembrane protein with multiple functions on glycemic
control, cell migration and proliferation, and the immune system, among others. It has …

Mechanistic understanding of the olfactory neuroepithelium involvement leading to short-term anosmia in COVID-19 using the adverse outcome pathway framework

MA Shahbaz, F De Bernardi, A Alatalo, M Sachana… - Cells, 2022 - mdpi.com
Loss of the sense of smell (anosmia) has been included as a COVID-19 symptom by the
World Health Organization. The majority of patients recover the sense of smell within a few …

Convergent evolution dynamics of SARS-CoV-2 and HIV surface envelope glycoproteins driven by host cell surface receptors and lipid rafts: lessons for the future

J Fantini, H Chahinian, N Yahi - International journal of molecular …, 2023 - mdpi.com
Although very different, in terms of their genomic organization, their enzymatic proteins, and
their structural proteins, HIV and SARS-CoV-2 have an extraordinary evolutionary potential …

How infection and vaccination are linked to acute and chronic urticaria: a special focus on COVID-19

E Kocatürk, M Muñoz, D Elieh-Ali-Komi, PR Criado… - Viruses, 2023 - mdpi.com
Since more than a century ago, there has been awareness of the connection between viral
infections and the onset and exacerbation of urticaria. Our knowledge about the role of viral …

Autoimmunity and immunodeficiency in severe SARS-CoV-2 infection and prolonged COVID-19

JV Garmendia, AH García, CV De Sanctis… - Current issues in …, 2022 - mdpi.com
SARS-CoV-2 causes the complex and heterogeneous illness known as COVID-19. The
disease primarily affects the respiratory system but can quickly become systemic, harming …

Intrinsic factors behind long‐COVID: I. Prevalence of the extracellular vesicles

YA El‐Maradny, A Rubio‐Casillas… - Journal of Cellular …, 2023 - Wiley Online Library
It can be argued that the severity of COVID‐19 has decreased in many countries. This could
be a result of the broad coverage of the population by vaccination campaigns, which often …

Human-derived air–liquid interface cultures decipher Alzheimer's disease–SARS-CoV-2 crosstalk in the olfactory mucosa

MA Shahbaz, S Kuivanen, R Lampinen… - Journal of …, 2023 - Springer
Background The neurological effects of the coronavirus disease of 2019 (COVID-19) raise
concerns about potential long-term consequences, such as an increased risk of Alzheimer's …

Impaired VEGF-A-mediated neurovascular crosstalk induced by SARS-CoV-2 spike protein: a potential hypothesis explaining long COVID-19 symptoms and COVID …

R Talotta - Microorganisms, 2022 - mdpi.com
Long coronavirus disease-19 (COVID-19) is a newly discovered syndrome characterized by
multiple organ manifestations that persist for weeks to months, following the recovery from …

[HTML][HTML] SARS-CoV-2 infection and immune responses

R Harne, B Williams, HFM Abdelaal, SL Baldwin… - AIMS …, 2023 - ncbi.nlm.nih.gov
The recent pandemic caused by the SARS-CoV-2 virus continues to be an enormous global
challenge faced by the healthcare sector. Availability of new vaccines and drugs targeting …

Tuberculosis and COVID-19 dually affect human Th17 cell immune response

A Starshinova, I Kudryavtsev, A Rubinstein, A Malkova… - Biomedicines, 2023 - mdpi.com
COVID-19 infection not only profoundly impacts the detection of tuberculosis infection (Tbc)
but also affects modality in tuberculosis patient immune response. It is important to …