Intermittent and periodic fasting, longevity and disease
Intermittent and periodic fasting (IF and PF, respectively) are emerging as safe strategies to
affect longevity and healthspan by acting on cellular aging and disease risk factors, while …
affect longevity and healthspan by acting on cellular aging and disease risk factors, while …
Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer's disease (AD): a systematic review and meta-analysis
Findings from previous studies reporting the levels of serum brain-derived neurotrophic
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …
[HTML][HTML] Metformin restores CNS remyelination capacity by rejuvenating aged stem cells
The age-related failure to produce oligodendrocytes from oligodendrocyte progenitor cells
(OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS) …
(OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS) …
Mitochondria as central regulators of neural stem cell fate and cognitive function
Emerging evidence now indicates that mitochondria are central regulators of neural stem
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …
cell (NSC) fate decisions and are crucial for both neurodevelopment and adult …
Neurogenesis in aging and age-related neurodegenerative diseases
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …
adult brain, declines in an age-dependent manner and is one potential target for extending …
[HTML][HTML] Nutritional factors affecting adult neurogenesis and cognitive function
SM Poulose, MG Miller, T Scott, B Shukitt-Hale - Advances in nutrition, 2017 - Elsevier
Adult neurogenesis, a complex process by which stem cells in the hippocampal brain region
differentiate and proliferate into new neurons and other resident brain cells, is known to be …
differentiate and proliferate into new neurons and other resident brain cells, is known to be …
Potential therapeutic uses of BDNF in neurological and psychiatric disorders
AH Nagahara, MH Tuszynski - Nature reviews Drug discovery, 2011 - nature.com
The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
Apoptosis in neurodegenerative disorders
MP Mattson - Nature reviews Molecular cell biology, 2000 - nature.com
Neuronal death underlies the symptoms of many human neurological disorders, including
Alzheimer's, Parkinson's and Huntington's diseases, stroke, and amyotrophic lateral …
Alzheimer's, Parkinson's and Huntington's diseases, stroke, and amyotrophic lateral …
Factors that influence adult neurogenesis as potential therapy
Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …
within distinct regions of the brain. This phenomenon was first described over 50 years ago …
Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the …
To determine the role of brain‐derived neurotrophic factor (BDNF) in the enhancement of
hippocampal neurogenesis resulting from dietary restriction (DR), heterozygous BDNF …
hippocampal neurogenesis resulting from dietary restriction (DR), heterozygous BDNF …