Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity

NN Koopaei, M Shademani, NS Yazdi, R Tahmasvand… - BMC chemistry, 2022 - Springer
Background Compounds possessing urea/thiourea moiety have a wide range of biological
properties including anticancer activity. On the other hand, taking advantage of the low …

Antiproliferative pharmacophore azo-hydrazone analogue BT-1F exerts death signalling pathway targeting STAT3 in solid tumour

Banumathi, A Sherapura, VH Malojirao, Zabiulla… - Pharmacological …, 2022 - Springer
Background Anomalous activation of intra-cellular signalling cascades confers neoplastic
properties on malignant cells. The JAK2/STAT3 proteins play a pivotal role in the …

Theoretical and experimental electronic transition behaviour study of 2-((4-(dimethylamino) benzylidene) amino)-4-methylphenol and its cytotoxicity

UD Uysal, D Ercengiz, O Karaosmanoğlu… - Journal of Molecular …, 2021 - Elsevier
In this study, a Schiff base (2-((4-(dimethylamino) benzylidene) amino)-4-methylphenol;
7S2) has been synthesized and characterized with 1 H, 13 C-NMR, IR and elemental …

Novel 1, 2, 3-Triazole Linked Chromene Hybrids: Microwave-Assisted Synthesis, Cytotoxic Activity, α-amylase Inhibitory Potential, Molecular Docking Analysis, and In …

A Hajlaoui, S Chortani, M Morjen, H Lazrag, Z Kibou… - Chemistry Africa, 2024 - Springer
This paper presents an efficient microwave-assisted synthesis of novel hybrid 1, 4-
disubstituted triazole derivatives under copper (I) catalyst. The formulas of the obtained …