Oxazole compounds containing nitrogen and oxygen atoms in the five-membered aromatic
ring are readily able to bind with a variety of enzymes and receptors in biological systems …

Compounds containing 1, 3, 4-oxadiazole ring in their structure are characterised by
multidirectional biological activity. Their anti-proliferative effects associated with various …

Due to the structure of acylhydrazones both by the pharmacophore–CO–NH–N= group and
by the different substituents present in the molecules of compounds of this class, various …

Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Abstract Five member heterocyclic 1, 3, 4-oxadiazole nucleus find unique place in medicinal
chemistry and plays significant role in producing anticancer activity. The small and simple 1 …

1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …

The world's health system is plagued by cancer and a worldwide effort is underway to find
new drugs to treat cancer. There has been a significant improvement in understanding the …

Telomerase is a ribonucleoprotein (RNP) responsible for the maintenance of chromosomal
integrity by stabilizing telomere length. Telomerase is a widely expressed hallmark …

Telomerase has emerged as an important primary target in anticancer therapy. It is a
distinctive reverse transcriptase enzyme, which extends the length of telomere at the 3 …

Abstract A series of1, 2, 4-and 1, 3, 4-oxadiazole derivatives were synthesized and
evaluated for their anticancer activity. Halogenated 1, 2, 4-oxadiazoles were obtained from …