This study aims to investigate the immune and epigenetic mutational landscape of
necroptosis in lung adenocarcinoma (LUAD), identify novel molecular phenotypes, and …

Background As a DNA surveillance mechanism, cell cycle checkpoint has recently been
discovered to be closely associated with lung adenocarcinoma (LUAD) prognosis. It is also …

Purpose TP53 mutation, one of the most frequent mutations in early‐stage lung
adenocarcinoma (LUAD), triggers a series of alterations in the immune landscape …

Background We aimed to assess whether recurrence patterns affect survival and to use a
multi-state model to predict the prognosis of early stage non-small cell lung cancer in …

Background and Aims. Histone deacetylase 1 (HDAC1) codes a protein that is a component
of the histone deacetylase complex. The abnormal expression of HDAC1 is strongly …

Purpose To evaluate the role of DSCC1 in LUAD. Patients and Methods Based on TCGA
and GTEx, the Wilcoxon rank-sum test was used to compare the expression differences of …

The immunogenomic features of tumor-adjacent lungs (TALs) in stage I lung squamous cell
carcinoma (LUSC) are not clear. Multiomics analyses of tumor tissues and paired TALs from …

The management of patients with advanced non-small cell lung cancer (NSCLC) presents
significant challenges due to cancer cells' intricate and heterogeneous nature. Programmed …

Background Lung adenocarcinoma accounts for the majority of lung cancer cases and
impact survival rate of patients severely. Immunotherapy is an effective treatment for lung …

Simple Summary Polygenic risk scores (PRSs) have been used to predict the risk of
developing cancer. However, whether PRSs are associated with immune infiltration in solid …