[HTML][HTML] Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis

Z Liu, Y Zhuang, L Fang, C Yuan, X Wang, K Lin - Bioactive Materials, 2023 - Elsevier
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

[HTML][HTML] Platelet-derived extracellular vesicles for regenerative medicine

M Antich-Rosselló, MA Forteza-Genestra… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) present a great potential for the development of new treatments
in the biomedical field. To be used as therapeutics, many different sources have been used …

[HTML][HTML] Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment

Y Sun, J Zhao, Q Wu, Y Zhang, Y You… - npj Regenerative …, 2022 - nature.com
Osteoarthritis (OA) is the leading cause of disability worldwide. Considerable progress has
been made using stem-cell-derived therapy. Increasing evidence has demonstrated that the …

[HTML][HTML] Advances in platelet rich plasma-derived extracellular vesicles for regenerative medicine: A systematic-narrative review

E Anitua, M Troya, JM Falcon-Pérez… - International Journal of …, 2023 - mdpi.com
The use of platelet-rich plasma (PRP) has gained increasing interest in recent decades. The
platelet secretome contains a multitude of growth factors, cytokines, chemokines, and other …

[HTML][HTML] Characterization and therapeutic use of extracellular vesicles derived from platelets

T Spakova, J Janockova, J Rosocha - International Journal of Molecular …, 2021 - mdpi.com
Autologous blood products, such as platelet-rich plasma (PRP), are gaining increasing
interest in different fields of regenerative medicine. Although growth factors, the main …

[HTML][HTML] Exosomes in the pathogenesis, progression, and treatment of osteoarthritis

Y Fan, Z Li, Y He - Bioengineering, 2022 - mdpi.com
Osteoarthritis (OA) is a prevalent and debilitating age-related joint disease characterized by
articular cartilage degeneration, synovial membrane inflammation, osteophyte formation, as …

[HTML][HTML] Extracellular vesicles and their potential significance in the pathogenesis and treatment of osteoarthritis

AM Mustonen, P Nieminen - Pharmaceuticals, 2021 - mdpi.com
Osteoarthritis (OA) is a chronic joint disease characterized by inflammation, gradual
destruction of articular cartilage, joint pain, and functional limitations that eventually lead to …

[HTML][HTML] Autologous platelet-and extracellular vesicle-rich plasma is an effective treatment modality for chronic postoperative temporal bone cavity inflammation …

D Vozel, D Božič, M Jeran, Z Jan, M Pajnič… - … in Bioengineering and …, 2021 - frontiersin.org
Purpose To determine the efficacy of autologous platelet-and extracellular vesicle-rich
plasma (PVRP) to treat chronic postoperative temporal bone cavity inflammation (CPTBCI) …

[HTML][HTML] Functional repertoire of EV-associated miRNA profiles after lipoprotein depletion via ultracentrifugation and size exclusion chromatography from autologous …

A Otahal, O Kuten-Pella, K Kramer, M Neubauer… - Scientific reports, 2021 - nature.com
Cartilage breakdown, inflammation and pain are hallmark symptoms of osteoarthritis, and
autologous blood products such as citrate-anticoagulated platelet-rich plasma (CPRP) or …

[HTML][HTML] The research progress of exosomes in osteoarthritis, with particular emphasis on the mediating roles of miRNAs and lncRNAs

C Miao, W Zhou, X Wang, J Fang - Frontiers in Pharmacology, 2021 - frontiersin.org
Osteoarthritis (OA) is a kind of degenerative disease, which is caused by many factors such
as aging, obesity, strain, trauma, congenital joint abnormalities, joint deformities. Exosomes …