Extracellular vesicles and their engineering strategies, delivery systems, and biomedical applications

C Yang, Y Xue, Y Duan, C Mao, M Wan - Journal of Controlled Release, 2024 - Elsevier
Extracellular vesicles are nanoscale vesicles that can be secreted by all cell types, are
intracellular in origin and have the same composition as their parent cells, play a key role in …

Algae: A robust living material against cancer

Z Xin, M Zhang, H Cui, X Ding, T Zhang… - International Journal …, 2023 - Taylor & Francis
Cancer is the second leading cause of death worldwide. Its incidence has been increasing
in recent years, and it is becoming a major threat to human health. Conventional cancer …

[HTML][HTML] Activation of autophagy by in situ Zn2+ chelation reaction for enhanced tumor chemoimmunotherapy

Y Yang, Y Zhu, K Wang, Y Miao, Y Zhang, J Gao… - Bioactive Materials, 2023 - Elsevier
Chemotherapy can induce a robust T cell antitumor immune response by triggering
immunogenic cell death (ICD), a process in which tumor cells convert from nonimmunogenic …

[HTML][HTML] Engineering preparation and sustained delivery of bone functional exosomes-laden biodegradable hydrogel for in situ bone regeneration

J Sun, G Li, S Wu, Y Zou, W Weng, T Gai… - Composites Part B …, 2023 - Elsevier
As an emerging cell-free therapy, exosomes derived from stem cells have been widely
explored for tissue regeneration. However, it is still a great challenge to achieve the …

Triple Cross‐linked Dynamic Responsive Hydrogel Loaded with Selenium Nanoparticles for Modulating the Inflammatory Microenvironment via PI3K/Akt/NF‐κB and …

S Wang, Y Liu, Q Sun, B Zeng, C Liu, L Gong… - Advanced …, 2023 - Wiley Online Library
Modulating the inflammatory microenvironment can inhibit the process of inflammatory
diseases (IDs). A tri‐cross‐linked inflammatory microenvironment‐responsive hydrogel with …

Microwave-activated Cu-doped zirconium metal-organic framework for a highly effective combination of microwave dynamic and thermal therapy

Y Feng, Q Chen, C Jin, Y Ruan, Q Chen, W Lin… - Journal of Controlled …, 2023 - Elsevier
Percutaneous microwave ablation (PMA) is a thermoablative method used as a minimally
invasive treatment for liver cancer. However, the application of PMA is limited by its …

Injectable Bioadhesive Photocrosslinkable Hydrogels with Sustained Release of Kartogenin to Promote Chondrogenic Differentiation and Partial‐Thickness Cartilage …

Q Han, J He, L Bai, Y Huang, B Chen… - Advanced …, 2024 - Wiley Online Library
Partial‐thickness cartilage defect (PTCD) is a common and formidable clinical challenge
without effective therapeutic approaches. The inherent anti‐adhesive characteristics of the …

Extracellular Matrix‐Mimetic Immunomodulatory Hydrogel for Accelerating Wound Healing

H Wang, R Huang, L Bai, Y Cai, M Lei… - Advanced …, 2023 - Wiley Online Library
Macrophages play a crucial role in the complete processes of tissue repair and
regeneration, and the activation of M2 polarization is an effective approach to provide a pro …

Biomembrane nanostructures: Multifunctional platform to enhance tumor chemoimmunotherapy via effective drug delivery

X Jiang, L Wu, M Zhang, T Zhang, C Chen, Y Wu… - Journal of Controlled …, 2023 - Elsevier
Chemotherapeutic drugs have been found to activate the immune response against tumors
by inducing immunogenic cell death, in addition to their direct cytotoxic effects toward …

Four‐Arm Polymer‐Guided Formation of Curcumin‐Loaded Flower‐Like Porous Microspheres as Injectable Cell Carriers for Diabetic Wound Healing

X Yuan, W Yang, Y Fu, Z Tao, L Xiao… - Advanced …, 2023 - Wiley Online Library
Stem cell injection is an effective approach for treating diabetic wounds; however, shear
stress during injections can negatively affect their stemness and cell growth. Cell‐laden …