Ultrafast magic angle spinning solid-state NMR spectroscopy: Advances in methodology and applications

Y Nishiyama, G Hou, V Agarwal, Y Su… - Chemical …, 2022 - ACS Publications
Solid-state NMR spectroscopy is one of the most commonly used techniques to study the
atomic-resolution structure and dynamics of various chemical, biological, material, and …

Predictive and mechanistic multivariate linear regression models for reaction development

CB Santiago, JY Guo, MS Sigman - Chemical science, 2018 - pubs.rsc.org
Multivariate Linear Regression (MLR) models utilizing computationally-derived and
empirically-derived physical organic molecular descriptors are described in this review …

Solid-state NMR: Methods for biological solids

S Ahlawat, KR Mote, NA Lakomek… - Chemical Reviews, 2022 - ACS Publications
In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

The magic of bicelles lights up membrane protein structure

UHN Dürr, M Gildenberg, A Ramamoorthy - Chemical reviews, 2012 - ACS Publications
Biological membranes and membrane proteins, responsible for numerous exciting
biological processes, present one of the paramount challenges in biophysics today …

Studying dynamics by magic-angle spinning solid-state NMR spectroscopy: Principles and applications to biomolecules

P Schanda, M Ernst - Progress in nuclear magnetic resonance …, 2016 - Elsevier
Magic-angle spinning solid-state NMR spectroscopy is an important technique to study
molecular structure, dynamics and interactions, and is rapidly gaining importance in …

Solid-state NMR dipolar and chemical shift anisotropy recoupling techniques for structural and dynamical studies in biological systems

L Liang, Y Ji, K Chen, P Gao, Z Zhao, G Hou - Chemical Reviews, 2022 - ACS Publications
With the development of NMR methodology and technology during the past decades, solid-
state NMR (ssNMR) has become a particularly important tool for investigating structure and …

Zinc ion rapidly induces toxic, off-pathway amyloid-β oligomers distinct from amyloid-β derived diffusible ligands in Alzheimer's disease

MC Lee, WC Yu, YH Shih, CY Chen, ZH Guo… - Scientific reports, 2018 - nature.com
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the elderly.
Zinc (Zn) ion interacts with the pathogenic hallmark, amyloid-β (Aβ), and is enriched in …

[HTML][HTML] NMR diffusion-encoding with axial symmetry and variable anisotropy: Distinguishing between prolate and oblate microscopic diffusion tensors with unknown …

S Eriksson, S Lasič, M Nilsson, CF Westin… - The Journal of …, 2015 - pubs.aip.org
We introduce a nuclear magnetic resonance method for quantifying the shape of axially
symmetric microscopic diffusion tensors in terms of a new diffusion anisotropy metric, D Δ …

Structure and assembly of filamentous bacteriophages

DA Marvin, MF Symmons, SK Straus - Progress in biophysics and …, 2014 - Elsevier
Filamentous bacteriophages are interesting paradigms in structural molecular biology, in
part because of the unusual mechanism of filamentous phage assembly. During assembly …

[PDF][PDF] Area per lipid and cholesterol interactions in membranes from separated local-field 13C NMR spectroscopy

A Leftin, TR Molugu, C Job, K Beyer, MF Brown - Biophysical journal, 2014 - cell.com
Investigations of lipid membranes using NMR spectroscopy generally require isotopic
labeling, often precluding structural studies of complex lipid systems. Solid-state 13 C magic …