Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …

Covering: 2008. Previous review: Nat. Prod. Rep., 2009, 26, 170This review covers the
literature published in 2008 for marine natural products, with 829 citations (613 for the …

Soft corals of the genus Sinularia are one of the most widespread soft corals. They are a rich
source of bioactive substances with intriguing and unique structural features. The present …

We investigated the three soft corals Sarcophyton stellatum, Capnella fungiformis and
Lobophytum crassum and the sponge Pseudoceratina arabica, which have been collected …

Covering: January 2007 to December 2008. Previous review: Nat. Prod. Rep., 2007, 24,
1332This review covers the isolation and chemistry of diterpenoids including labdanes …

Invasion and metastasis, the hallmark of malignant tumor, is the main reason for the clinical
death of most cancer patients. Tumor invasion and metastasis are complex, multi-step …

Highlights•Modern drug discovery efforts are leaning toward natural product-based
scaffolds.•Marine natural products exemplify novel resources for new drugs.•Marine …

The in-vitro anti-proliferative evaluation of Sinularia levi total extract against three cell lines
revealed its potent effect against Caco-2 cell line with IC50 3.3 μg/mL, followed by MCF-7 …

Marine organisms are recognized as a rich source of bioactive secondary metabolites. The
remarkable abundance and diversity of bioactive small molecules isolated from soft corals …

Bioassay-guided fractionation of the marine sponge Lendenfeldia dendyi and the soft coral
Sinularia dura resulted in the isolation of five polybrominated diphenyl ethers (1–5). The …