The knowns and unknowns of neural adaptations to resistance training
The initial increases in force production with resistance training are thought to be primarily
underpinned by neural adaptations. This notion is firmly supported by evidence displaying …
underpinned by neural adaptations. This notion is firmly supported by evidence displaying …
Testing the excitability of human motoneurons
The responsiveness of the human central nervous system can change profoundly with
exercise, injury, disuse, or disease. Changes occur at both cortical and spinal levels but in …
exercise, injury, disuse, or disease. Changes occur at both cortical and spinal levels but in …
Group III/IV locomotor muscle afferents alter motor cortical and corticospinal excitability and promote central fatigue during cycling exercise
Objective To investigate the influence of group III/IV muscle afferents on the development of
central fatigue and corticospinal excitability during exercise. Methods Fourteen males …
central fatigue and corticospinal excitability during exercise. Methods Fourteen males …
Stimulation of the motor cortex and corticospinal tract to assess human muscle fatigue
This review aims to characterize fatigue-related changes in corticospinal excitability and
inhibition in healthy subjects. Transcranial magnetic stimulation (TMS) has been extensively …
inhibition in healthy subjects. Transcranial magnetic stimulation (TMS) has been extensively …
Critical considerations of the contribution of the corticomotoneuronal pathway to central fatigue
Neural drive originating in higher brain areas reaches exercising limb muscles through the
corticospinal‐motoneuronal pathway, which links the motor cortex and spinal …
corticospinal‐motoneuronal pathway, which links the motor cortex and spinal …
Neurophysiological mechanisms underpinning stretch-induced force loss
It is well known that prolonged passive muscle stretch reduces maximal muscle force
production. There is a growing body of evidence suggesting that adaptations occurring …
production. There is a growing body of evidence suggesting that adaptations occurring …
Multisite Hebbian plasticity restores function in humans with spinal cord injury
Objective Spinal cord injury (SCI) damages synaptic connections between corticospinal
axons and motoneurons of many muscles, resulting in devastating paralysis. We …
axons and motoneurons of many muscles, resulting in devastating paralysis. We …
Motoneuron responsiveness to corticospinal tract stimulation during the silent period induced by transcranial magnetic stimulation
AF Yacyshyn, EJ Woo, MC Price, CJ McNeil - Experimental brain research, 2016 - Springer
Based on H-reflex data, spinal mechanisms are proposed to be responsible for the first 50–
80 ms of the transcranial magnetic stimulation (TMS)-induced silent period. As several …
80 ms of the transcranial magnetic stimulation (TMS)-induced silent period. As several …
Effects of fatigue on corticospinal excitability of the human knee extensors
DS Kennedy, CJ McNeil, SC Gandevia… - Experimental …, 2016 - Wiley Online Library
New Findings What is the central question of this study? Do group III and IV muscle afferents
act at the spinal or cortical level to affect the ability of the central nervous system to drive …
act at the spinal or cortical level to affect the ability of the central nervous system to drive …
Can local vibration alter the contribution of persistent inward currents to human motoneuron firing?
The response of spinal motoneurons to synaptic input greatly depends on the activation of
persistent inward currents (PICs), which in turn are enhanced by the neuromodulators …
persistent inward currents (PICs), which in turn are enhanced by the neuromodulators …