Plasmodium parasites have a complex life cycle alternating between a mosquito and a
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …

Malaria is a febrile illness caused by species of the protozoan parasite Plasmodium and is
characterized by recursive infections of erythrocytes, leading to clinical symptoms and …

Intracellular malaria parasites grow in a vacuole delimited by the parasitophorous vacuolar
membrane (PVM). This membrane fulfils critical roles for survival of the parasite in its …

Intraerythrocytic malaria parasites reside within a parasitophorous vacuole membrane
(PVM) that closely overlays the parasite plasma membrane. Although the PVM is the site of …

Relapses of Plasmodium dormant liver hypnozoites compromise malaria eradication efforts.
New radical cure drugs are urgently needed, yet the vast gap in knowledge of hypnozoite …

Plasmodium parasites undergo an obligatory and asymptomatic developmental stage within
the liver before infecting red blood cells to cause malaria. The hijacked host pathways …

The intracellular development and differentiation of the Plasmodium parasite in the host liver
is a prerequisite for the actual onset of malaria disease pathology. Since liver-stage infection …

Recent years have witnessed a great gain in knowledge regarding parasite–host cell
interactions during Plasmodium liver stage development. It is now an accepted fact that a …

Hepatocystis is a genus of single-celled parasites infecting, amongst other hosts, monkeys,
bats and squirrels. Although thought to have descended from malaria parasites …

Aerolysins initially characterized as virulence factors in bacteria are increasingly found in
massive genome and transcriptome sequencing data from metazoans. Horizontal gene …