Candidate proteomic biomarker discovery from human plasma holds both incredible clinical
potential as well as significant challenges. The dynamic range of proteins within plasma is …

Mammalian cell surfaces are all covered with bioactive oligosaccharides which play an
important role in molecular recognition events such as immune recognition, cell–cell …

The incorporation of C‐glycosides in drug design has become a routine practice for
medicinal chemists. These naturally occurring building blocks exhibit attractive …

Ratiometric fluorescence sensing is a useful technique for the precise and quantitative
analysis of biological events occurring under complex conditions, such as those inside cells …

Motivation Carbohydrate Active enzyme (CAZyme) families, encoded by human gut
microflora, play a crucial role in breakdown of complex dietary carbohydrates into …

Hexofuranosides are widely spread in nature, and notably in numerous pathogenic
microorganisms. This particular five-membered ring for hexosides leads to novel biological …

In this study, a facile and efficient method to synthesize monofluoroalkenes by photoredox
catalytic defluorinative alkylation of gem-difluoroalkenes with 4-alkyl-1, 4-dihydropyridines …

Amino acids/peptide conjugated heterocycles represent an important class of therapeutical
agents. Biologically active heterocycles are conjugated with amino acids or peptides to …

In an effort to explore the contribution of the sugar constituents of pharmaceutically relevant
glycosylated natural products, chemists have developed glycosylation methods that are …

The genomes of eleven Gram-positive bacteria that are important for human health and the
food industry, nine low G+ C lactic acid bacteria and two high G+ C Gram-positive …