The adenosine A2A receptor subtype is recognized as a non-dopaminergic
pharmacological target for the treatment of neurodegenerative disorders, notably …

Adenosine, acting both through G-protein coupled adenosine receptors and intracellularly,
plays a complex role in multiple physiological and pathophysiological processes by …

Abstract L-DOPA-induced dyskinesia (LID) is a significant complication of dopamine
replacement therapy in Parkinson's disease (PD), and the specific role of different dopamine …

Alzheimer's and Parkinson's are neurodegenerative disorders that affect a great number of
people around the world, seriously compromising the quality of life of individuals, due to …

Abstract Introduction Adenosine 2A (A2A) receptors co-localize with dopamine D2 receptors
in striatopallidal medium spiny neurons of the indirect pathway. A2A receptor activation in …

Adenosine levels are important in various physiological and pathological activities, but
detecting them is difficult because of interference from a complex matrix. This study …

Rationale Withdrawal from chronic alcohol exposure produces various physical and mental
withdrawal symptoms. Activation of adenosine receptors is known to inhibit withdrawal …

Hintergrund Patienten mit einem idiopathischen Parkinson-Syndrom können offenbar vom
Koffeinkonsum profitieren, wie bereits eine Reihe experimenteller und klinischer Studien …

Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is
generally accepted that dopamine replacement therapy substantially improves motor …

Controversies regarding benefits and risks of coffee consumption still exist, but the limitless
health-promoting benefits of coffee outclass its few reported toxic effects. This study is …