The emerging treatment landscape of targeted therapy in non-small-cell lung cancer

M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
Lung cancer is one of the most common cancer in the world. In 2018, there were over 2
million new cases of lung cancer and over 1.7 million deaths were attributed to lung cancer …

Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

D Planchard, ST Popat, K Kerr, S Novello… - Annals of …, 2018 - annalsofoncology.org
Primary lung cancer remains the most common malignancy after non-melanocytic skin
cancer, and deaths from lung cancer exceed those from any other malignancy worldwide [1] …

Non–small cell lung cancer, version 5.2017, NCCN clinical practice guidelines in oncology

DS Ettinger, DE Wood, DL Aisner, W Akerley… - Journal of the National …, 2017 - jnccn.org
This selection from the NCCN Guidelines for Non–Small Cell Lung Cancer (NSCLC)
focuses on targeted therapies and immunotherapies for metastatic NSCLC, because …

Correction to:“Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up”

D Planchard, S Popat, K Kerr, S Novello… - Annals of …, 2019 - annalsofoncology.org
1. In KEYNOTE-189, patients with metastatic non-squamous NSCLC, PS 0-1, without
sensitising EGFR or ALK mutations, were randomised to receive pemetrexed and a platinum …

[HTML][HTML] Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO–ESMO initiative endorsed …

YL Wu, D Planchard, S Lu, H Sun, N Yamamoto… - Annals of …, 2019 - Elsevier
The most recent version of the European Society for Medical Oncology (ESMO) Clinical
Practice Guidelines for the diagnosis, treatment and follow-up of metastatic non-small-cell …

[HTML][HTML] Current and emergent therapy options for advanced squamous cell lung cancer

MA Socinski, C Obasaju, D Gandara, FR Hirsch… - Journal of Thoracic …, 2018 - Elsevier
Squamous cell lung cancer (SqCLC) is a distinct histologic subtype of NSCLC that is
challenging to treat because of specific clinicopathologic characteristics, which include older …

The Japanese Lung Cancer Society Guideline for non-small cell lung cancer, stage IV

H Akamatsu, K Ninomiya, H Kenmotsu… - International journal of …, 2019 - Springer
According to rapid development of chemotherapy in advanced non-small cell lung cancer
(NSCLC), the Japan Lung Cancer Society has been updated its own guideline annually …

Tyrosine kinase receptors in oncology

J Esteban-Villarrubia, JJ Soto-Castillo, J Pozas… - International journal of …, 2020 - mdpi.com
Tyrosine kinase receptors (TKR) comprise more than 60 molecules that play an essential
role in the molecular pathways, leading to cell survival and differentiation. Consequently …

[HTML][HTML] EGFRvIII: An Oncogene with Ambiguous Role

A Rutkowska, E Stoczyńska-Fidelus, K Janik… - Journal of …, 2019 - hindawi.com
Epidermal growth factor receptor variant III (EGFR vIII) seems to constitute the perfect
therapeutic target for glioblastoma (GB), as it is specifically present on up to 28–30% of GB …

Lung cancer costs by treatment strategy and phase of care among patients enrolled in Medicare

DF Sheehan, SD Criss, Y Chen, A Eckel… - Cancer …, 2019 - Wiley Online Library
Background We studied trends in lung cancer treatment cost over time by phase of care,
treatment strategy, age, stage at diagnosis, and histology. Methods Using the Surveillance …