[HTML][HTML] Free fatty acid receptors in health and disease

I Kimura, A Ichimura, R Ohue-Kitano… - Physiological …, 2019 - journals.physiology.org
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …

Taste buds: cells, signals and synapses

SD Roper, N Chaudhari - Nature Reviews Neuroscience, 2017 - nature.com
The past decade has witnessed a consolidation and refinement of the extraordinary
progress made in taste research. This Review describes recent advances in our …

Taste of fat: a sixth taste modality?

P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …

Taste preference for fatty acids is mediated by GPR40 and GPR120

C Cartoni, K Yasumatsu, T Ohkuri… - Journal of …, 2010 - Soc Neuroscience
The oral perception of fat has traditionally been considered to rely mainly on texture and
olfaction, but recent findings suggest that taste may also play a role in the detection of long …

The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects

MY Pepino, L Love-Gregory, S Klein… - Journal of lipid …, 2012 - ASBMB
The precise orosensory inputs engaged for dietary lipids detection in humans are unknown.
We evaluated whether a common single nucleotide polymorphism (rs1761667) in the CD36 …

Flavor chemistry of virgin olive oil: An overview

A Genovese, N Caporaso, R Sacchi - Applied Sciences, 2021 - mdpi.com
Virgin olive oil (VOO) has unique chemical characteristics among all other vegetable oils
which are of paramount importance for human health. VOO constituents are also …

G protein–coupled receptors in human fat taste perception

MM Galindo, N Voigt, J Stein, J van Lengerich… - Chemical …, 2012 - academic.oup.com
In contrast to carbohydrates and proteins, which are detected by specialized taste receptors
in the forms of their respective building blocks, sugars, and l-amino acids, the third …

Role of free fatty acid receptors in the regulation of energy metabolism

T Hara, D Kashihara, A Ichimura, I Kimura… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Free fatty acids (FFAs) are energy-generating nutrients that act as signaling molecules in
various cellular processes. Several orphan G protein-coupled receptors (GPCRs) that act as …

Genetics of taste and smell: poisons and pleasures

DR Reed, A Knaapila - Progress in molecular biology and translational …, 2010 - Elsevier
Eating is dangerous. While food contains nutrients and calories that animals need to
produce heat and energy, it may also contain harmful parasites, bacteria, or chemicals. To …

Free fatty acid (FFA) and hydroxy carboxylic acid (HCA) receptors

S Offermanns - Annual review of pharmacology and toxicology, 2014 - annualreviews.org
Saturated and unsaturated free fatty acids (FFAs), as well as hydroxy carboxylic acids
(HCAs) such as lactate and ketone bodies, are carriers of metabolic energy, precursors of …