In-depth structural characterization of lipids is an essential component of lipidomics. There
has been a rapid expansion of mass spectrometry methods that are capable of resolving …

This article highlights, to our opinion, some of the most pertinent issues related to producing
high quality lipidomics data. These issues include pitfalls related to sample collection and …

Mass spectrometry imaging (MSI) enables the spatial distributions of molecules possessing
different mass‐to‐charge ratios to be mapped within complex environments revealing …

The chemical complexity of biological tissues creates challenges in the analysis of lipids via
imaging mass spectrometry. The presence of isobaric and isomeric compounds introduces …

Lipids are a structurally diverse class of molecules with important biological functions
including cellular signaling and energy storage. Matrix-assisted laser desorption/ionization …

Desorption electrospray ionization (DESI) mass spectrometry imaging has become a
powerful strategy for analysis of tissue sections, enabling differentiation of normal and …

As a major class of mammalian lipids, phosphatidylcholines (PCs) often contain mixtures of
structural isomers, resulting from different lipogenesis pathways. Profiling PCs at the isomer …

Biofluid metabolomics is a popular tool for biomarker discovery to decipher disease-,
genetics-, and exposure-related metabolic alterations and is an essential component for …

As the field of lipidomics grows and its application becomes wide and varied it is important
that we don't forget its foundation, ie the identification and measurement of molecular lipids …

Phospholipids are major components of most eukaryotic cell membranes. Changes in
metabolic states are often accompanied by phospholipid structure variations. The structural …