The search for noise-induced cochlear synaptopathy in humans: Mission impossible?

N Bramhall, EF Beach, B Epp, CG Le Prell… - Hearing research, 2019 - Elsevier
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …

[HTML][HTML] Tinnitus: does gain explain?

W Sedley - Neuroscience, 2019 - Elsevier
Many, or most, tinnitus models rely on increased central gain in the auditory pathway as all
or part of the explanation, in that central auditory neurones deprived of their usual sensory …

[HTML][HTML] Hidden hearing loss? No effect of common recreational noise exposure on cochlear nerve response amplitude in humans

SK Grinn, KB Wiseman, JA Baker… - Frontiers in …, 2017 - frontiersin.org
This study tested hypothesized relationships between noise exposure and auditory deficits.
Both retrospective assessment of potential associations between noise exposure history and …

Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans

KL Marks, DT Martel, C Wu, GJ Basura… - Science Translational …, 2018 - science.org
The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian
auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve …

The effects of noise exposure and musical training on suprathreshold auditory processing and speech perception in noise

I Yeend, EF Beach, M Sharma, H Dillon - Hearing research, 2017 - Elsevier
Recent animal research has shown that exposure to single episodes of intense noise
causes cochlear synaptopathy without affecting hearing thresholds. It has been suggested …

Non-invasive assays of cochlear synaptopathy–candidates and considerations

HM Bharadwaj, AR Mai, JM Simpson, I Choi, MG Heinz… - Neuroscience, 2019 - Elsevier
Studies in multiple species, including in post-mortem human tissue, have shown that normal
aging and/or acoustic overexposure can lead to a significant loss of afferent synapses …

Hidden hearing loss: a disorder with multiple etiologies and mechanisms

DC Kohrman, G Wan… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
Hidden hearing loss (HHL), a recently described auditory disorder, has been proposed to
affect auditory neural processing and hearing acuity in subjects with normal audiometric …

Effects of noise exposure on auditory brainstem response and speech-in-noise tasks: A review of the literature

CG Le Prell - International journal of audiology, 2019 - Taylor & Francis
Objective: Short-term noise exposure that induces transient changes in thresholds has
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …

The stochastic resonance model of auditory perception: A unified explanation of tinnitus development, Zwicker tone illusion, and residual inhibition

A Schilling, K Tziridis, H Schulze, P Krauss - Progress in brain research, 2021 - Elsevier
Stochastic resonance (SR) has been proposed to play a major role in auditory perception,
and to maintain optimal information transmission from the cochlea to the auditory system. By …

Tinnitus and auditory perception after a history of noise exposure: Relationship to auditory brainstem response measures

NF Bramhall, D Konrad-Martin, GP McMillan - Ear and hearing, 2018 - journals.lww.com
Objectives: To determine whether auditory brainstem response (ABR) wave I amplitude is
associated with measures of auditory perception in young people with normal distortion …