Diagnosis for latent tuberculosis infection: new alternatives

C Carranza, S Pedraza-Sanchez… - Frontiers in …, 2020 - frontiersin.org
Latent tuberculosis infection (LTBI) is a subclinical mycobacterial infection defined on the
basis of cellular immune response to mycobacterial antigens. The tuberculin skin test (TST) …

YY1 regulates cancer cell immune resistance by modulating PD-L1 expression

E Hays, B Bonavida - Drug Resistance Updates, 2019 - Elsevier
Recent advances in the treatment of various cancers have resulted in the adaptation of
several novel immunotherapeutic strategies. Notably, the recent intervention through …

IFI44L as a forward regulator enhancing host antituberculosis responses

H Jiang, L Tsang, H Wang, C Liu - Journal of Immunology …, 2021 - Wiley Online Library
Interferon‐induced protein 44‐like (IFI44L) gene is a type I interferon‐stimulated gene (ISG)
that plays a critical role in antiviral activity and constitutes a promising diagnostic marker …

Identification and classification of differentially expressed genes and network meta-analysis reveals potential molecular signatures associated with tuberculosis

A Alam, N Imam, MM Ahmed, S Tazyeen… - Frontiers in …, 2019 - frontiersin.org
Tuberculosis (TB) is one of deadly transmissible disease that causes death worldwide;
however, only 10% of people infected with Mycobacterium tuberculosis develop disease …

YY1: a novel therapeutic target for diabetic nephropathy orchestrated renal fibrosis

T Yang, F Shu, H Yang, C Heng, Y Zhou, Y Chen… - Metabolism, 2019 - Elsevier
Background Renal fibrosis promotes the development of diabetic nephropathy (DN). A
growing number of studies have reported that Yin Yang 1 (YY1), which is involved in cellular …

PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection

SM Borbora, RS Rajmani, KN Balaji - PLoS pathogens, 2022 - journals.plos.org
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), triggers
enhanced accumulation of lipids to generate foamy macrophages (FMs). This process has …

Dual role of hypoxia-inducible factor 1 α in experimental pulmonary tuberculosis: Its implication as a new therapeutic target

GJ Baay-Guzman, MA Duran-Padilla… - Future …, 2018 - Taylor & Francis
Aim: Investigate the role of hypoxia-inducible factor-1α (HIF-1α) in pulmonary tuberculosis
(TB). Methods & results: A model of progressive pulmonary TB in BALB/c mice …

Expression of USP18 and IL2RA is increased in individuals receiving latent tuberculosis treatment with isoniazid

E de Oyarzabal, L García-García… - Journal of …, 2019 - Wiley Online Library
Background. The treatment of latent tuberculosis infection (LTBI) in individuals at risk of
reactivation is essential for tuberculosis control. However, blood biomarkers associated with …

Effect of IL-17A on the immune response to pulmonary tuberculosis induced by high- and low-virulence strains of Mycobacterium bovis

Y Rodríguez-Míguez, V Lozano-Ordaz… - Plos one, 2024 - journals.plos.org
Tuberculosis (TB) is an infectious, chronic, and progressive disease occurring globally.
Human TB is caused mainly by Mycobacterium tuberculosis (M. tuberculosis), while the …

Physical interaction of human Yin Yang 1 protein with DNA

M Figiel, A Górecki - Critical Reviews™ in Oncogenesis, 2017 - dl.begellhouse.com
ABSTRACT Yin Yang 1 (YY1)'s interaction with DNA can result in various, even
contradicting, effects on transcription in the form of initiation, activation, or repression. This …