During the last decades, schizophrenia has been regarded as a developmental disorder.
The neurodevelopmental hypothesis proposes schizophrenia to be related to genetic and …

Insulin and insulin-like growth factor 1 (IGF1) signalling play a central role in the
development and maintenance of neurons in the brain, and in humans neurodevelopmental …

Recent studies suggest that genetic and environmental factors do not account for all the
schizophrenia risk, and epigenetics also has a role in disease susceptibility. DNA …

Increased peripheral levels of morning cortisol have been reported in people with
schizophrenia (SZ) and bipolar disorder (BD), but findings are inconsistent and few studies …

Maternal stress and medical illnesses during early life are well-documented environmental
indicators of an increased risk of schizophrenia. Few studies, conversely, have confirmed an …

In the past decades, cutting-edge research techniques have facilitated better understanding
of the bi-directional 'vectors of influence'that link the genes, brain and social behavior. This …

Although the etiology of schizophrenia (SZ) remains unknown, it is increasingly clear that
immune dysregulation plays a central role. Genome-wide association studies reproducibly …

Endocannabinoids regulate brain development via modulating neural proliferation,
migration, and the differentiation of lineage-committed cells. In the fetal nervous …

Micro RNA (miRNA) research has great implications in uncovering the aetiology of
neuropsychiatric conditions due to the role of miRNA in brain development and function …

Background Severe mental illnesses like schizophrenia and bipolar disorder are known to
be diseases that to some extent, but not entirely can be understood genetically. The …