Controlling ticks and tick-borne diseases… looking forward

J de la Fuente - Ticks and tick-borne diseases, 2018 - Elsevier
Tick-borne diseases (TBDs) represent a growing burden for human and animal health
worldwide. Several approaches including the use of chemicals with repellency and …

Chemotaxis-Instructed Intracellular Staphylococcus aureus Infection Detection by a Targeting and Self-Assembly Signal-Enhanced Photoacoustic Probe

Q Cai, Y Fei, L Hu, Z Huang, LL Li, H Wang - Nano letters, 2018 - ACS Publications
Intracellular invasion and the survival of Staphylococcus aureus in phagocytic cells has
been regarded as one of the mechanisms that leads to the treatment failure of S. aureus …

Recent advances in genetic systems in obligate intracellular human-pathogenic bacteria

DJ Fisher, PA Beare - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
The ability to genetically manipulate a pathogen is fundamental to discovering factors
governing host–pathogen interactions at the molecular level and is critical for devising …

The “Biological Weapons” of Ehrlichia chaffeensis: Novel Molecules and Mechanisms to Subjugate Host Cells

Y Rikihisa - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic
ehrlichiosis, an emerging, potentially fatal tick-borne infectious disease. The bacterium …

The enigmatic biology of rickettsiae: recent advances, open questions and outlook

J McGinn, RL Lamason - Pathogens and Disease, 2021 - academic.oup.com
Rickettsiae are obligate intracellular bacteria that can cause life-threatening illnesses and
are among the oldest known vector-borne pathogens. Members of this genus are …

The transporter-mediated cellular uptake and efflux of pharmaceutical drugs and biotechnology products: how and why phospholipid bilayer transport is negligible in …

DB Kell - Molecules, 2021 - mdpi.com
Over the years, my colleagues and I have come to realise that the likelihood of
pharmaceutical drugs being able to diffuse through whatever unhindered phospholipid …

Targeted drug delivery systems for eliminating intracellular bacteria

W Feng, M Chittò, TF Moriarty, G Li… - Macromolecular …, 2023 - Wiley Online Library
The intracellular survival of pathogenic bacteria requires a range of survival strategies and
virulence factors. These infections are a significant clinical challenge, wherein treatment …

[HTML][HTML] Frankenbacteriosis targeting interactions between pathogen and symbiont to control infection in the tick vector

L Mazuecos, P Alberdi, A Hernández-Jarguín… - Iscience, 2023 - cell.com
Tick microbiota can be targeted for the control of tick-borne diseases such as human
granulocytic anaplasmosis (HGA) caused by model pathogen, Anaplasma …

Applications of bacteriophages against intracellular bacteria

P Śliwka, M Ochocka… - Critical Reviews in …, 2022 - Taylor & Francis
Infectious diseases pose a significant threat to both human and animal populations.
Intracellular bacteria are a group of pathogens that invade and survive within the interior of …

The burden of the serious and difficult-to-treat infections and a new antibiotic available: cefiderocol

Y Taheri, N Joković, J Vitorović… - Frontiers in …, 2021 - frontiersin.org
Background: Infection is a disease that can occur due to the entrance of a virus, bacteria,
and other infectious agents. Cefiderocol is innovative cephalosporin drug that belongs to a …