A bioinspired hierarchical nanoplatform targeting and responding to intracellular pathogens to eradicate parasitic infections
Y Yu, J Li, Y Zhang, Z Ma, H Sun, X Wei, Y Bai, Z Wu… - Biomaterials, 2022 - Elsevier
Intracellular bacteria-mediated antibiotic tolerance, which acts as a “Trojan horse,” plays a
critical and underappreciated role in chronic and recurrent infections. Failure of conventional …
critical and underappreciated role in chronic and recurrent infections. Failure of conventional …
Forward genetics in Wolbachia: Regulation of Wolbachia proliferation by the amplification and deletion of an addictive genomic island
EH Duarte, A Carvalho, S López-Madrigal, J Costa… - PLoS …, 2021 - journals.plos.org
Wolbachia is one of the most prevalent bacterial endosymbionts, infecting approximately
40% of terrestrial arthropod species. Wolbachia is often a reproductive parasite but can also …
40% of terrestrial arthropod species. Wolbachia is often a reproductive parasite but can also …
Advances in genetic manipulation of Chlamydia trachomatis
W Wan, D Li, D Li, J Jiao - Frontiers in Immunology, 2023 - frontiersin.org
Chlamydia trachomatis, one species of Chlamydia spp., has the greatest impact on human
health and is the main cause of bacterial sexually transmitted diseases and preventable …
health and is the main cause of bacterial sexually transmitted diseases and preventable …
Why new vaccines for the control of ectoparasite vectors have not been registered and commercialized?
J de la Fuente, A Estrada-Peña - Vaccines, 2019 - mdpi.com
The prevention and control of vector-borne diseases is a priority for improving global health.
Despite recent advances in the characterization of ectoparasite-host-pathogen molecular …
Despite recent advances in the characterization of ectoparasite-host-pathogen molecular …
Evolutionary insights into the tick hologenome
Recently, our knowledge of the composition and complexity of tick microbial communities
has increased and supports microbial impact on tick biology. Results support a phylogenetic …
has increased and supports microbial impact on tick biology. Results support a phylogenetic …
The immune-suppressive landscape in lepromatous leprosy revealed by single-cell RNA sequencing
Z Mi, Z Wang, X Xue, T Liu, C Wang, L Sun, G Yu… - Cell discovery, 2022 - nature.com
Abstract Lepromatous leprosy (L-LEP), caused by the massive proliferation of
Mycobacterium leprae primarily in macrophages, is an ideal disease model for investigating …
Mycobacterium leprae primarily in macrophages, is an ideal disease model for investigating …
Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation
Ehrlichia chaffeensis, an obligatory intracellular bacterium, infects monocytes/macrophages
by sequestering a regulator of endosomal traffic, the small GTPase RAB5, on its membrane …
by sequestering a regulator of endosomal traffic, the small GTPase RAB5, on its membrane …
Unpacking the intricacies of Rickettsia–vector interactions
HJ Laukaitis, KR Macaluso - Trends in parasitology, 2021 - cell.com
Although Rickettsia species are molecularly detected among a wide range of arthropods,
vector competence becomes an imperative aspect of understanding the ecoepidemiology of …
vector competence becomes an imperative aspect of understanding the ecoepidemiology of …
Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses
Orientia tsutsugamushi is an obligately intracellular bacterium and the etiological agent of
scrub typhus. The lung is a major target organ of infection, displaying type 1-skewed …
scrub typhus. The lung is a major target organ of infection, displaying type 1-skewed …
An Anaplasma phagocytophilum T4SS effector, AteA, is essential for tick infection
JM Park, BM Genera, D Fahy, KT Swallow, CM Nelson… - Mbio, 2023 - Am Soc Microbiol
Pathogens must adapt to disparate environments in permissive host species, a feat that is
especially pronounced for vector-borne microbes, which transition between vertebrate hosts …
especially pronounced for vector-borne microbes, which transition between vertebrate hosts …