An expanded genetic toolkit for inducible expression and targeted gene silencing in Rickettsia parkeri

J McGinn, A Wen, DL Edwards, DM Brinkley… - Journal of …, 2024 - Am Soc Microbiol
Pathogenic species within the Rickettsia genus are transmitted to humans through arthropod
vectors and cause a spectrum of diseases ranging from mild to life-threatening. Despite …

Transdermal Delivery of Photosensitizer‐Catalase Conjugate by Fluorinated Polyethylenimine for Enhanced Topical Photodynamic Therapy of Bacterial Infections

H Wang, Y Xie, Y Chen, H Zhao, X Lv… - Advanced …, 2023 - Wiley Online Library
Pathogenic bacteria induce subcutaneous infections pose serious threats to global public
health. Recently, photodynamic therapy (PDT) has been proposed as a non‐invasive …

Identification of Anaplasma marginale adhesins for entry into Dermacentor andersoni tick cells using phage display

SM Noh, J Ujczo, DC Alperin, SM Jarvis… - Infection and …, 2024 - Am Soc Microbiol
Anaplasma marginale is an obligate, intracellular, tick-borne bacterial pathogen that causes
bovine anaplasmosis, an often severe, production-limiting disease of cattle found worldwide …

[HTML][HTML] Cell-selective proteomics reveal novel effectors secreted by an obligate intracellular bacterial pathogen

AG Sanderlin, HK Margolis, AF Meyer, RL Lamason - bioRxiv, 2023 - ncbi.nlm.nih.gov
Pathogenic bacteria secrete protein effectors to hijack host machinery and remodel their
infectious niche. Rickettsia spp. are obligate intracellular bacteria that can cause life …

[HTML][HTML] Multiple Ehrlichia chaffeensis genes critical for persistent infection in a vertebrate host are identified as nonessential for its growth in the tick vector; …

DC Jaworski, Y Wang, A Nair, H Liu… - Frontiers in Cellular and …, 2023 - frontiersin.org
Ehrlichia chaffeensis is a tick-transmitted monocytic ehrlichiosis agent primarily causing the
disease in people and dogs. We recently described the development and characterization of …

Cascade encapsulation of antimicrobial peptides, exosomes and antibiotics in fibrin-gel for first-aid hemostasis and infected wound healing

LY Su, M Yao, W Xu, M Zhong, Y Cao… - International Journal of …, 2024 - Elsevier
Wounding is one of the most common healthcare problems. Bioactive hydrogels have
attracted much attention in first-aid hemostasis and wound healing due to their excellent …

[HTML][HTML] Host-directed therapy for bacterial infections-Modulation of the phagolysosome pathway

T Taya, F Teruyama, S Gojo - Frontiers in Immunology, 2023 - frontiersin.org
Bacterial infections still impose a significant burden on humanity, even though antimicrobial
agents have long since been developed. In addition to individual severe infections, the f …

Strategies for the eradication of intracellular bacterial pathogens

Y Chen, Y Jiang, T Xue, J Cheng - Biomaterials Science, 2024 - pubs.rsc.org
Intracellular pathogens affect a significant portion of world population and cause millions of
deaths each year. They can invade host cells and survive inside them and are extremely …

Characterization of Burkholderia bacteria clade compositions in soil and Riptortus pedestris (Hemiptera: Alydidae) in South Korea

JY Kim, M Jung, DH Lee - Journal of Asia-Pacific Entomology, 2022 - Elsevier
Abstract Riptortus pedestris (Hemiptera: Alydidae) is known to acquire the genus
Burkholderia, symbiotic bacteria, from soil. Therefore, symbiont acquisition of R. pedestris …

Biostatistical prediction of genes essential for growth of Anaplasma phagocytophilum in a human promyelocytic cell line using a random transposon mutant library

MC O'Conor, MJ Herron, CM Nelson… - Pathogens and …, 2021 - academic.oup.com
Anaplasma phagocytophilum (Ap), agent of human anaplasmosis, is an intracellular
bacterium that causes the second most common tick-borne illness in North America. To …