Artificial intelligence to deep learning: machine intelligence approach for drug discovery
Drug designing and development is an important area of research for pharmaceutical
companies and chemical scientists. However, low efficacy, off-target delivery, time …
companies and chemical scientists. However, low efficacy, off-target delivery, time …
Virology, epidemiology, pathogenesis, and control of COVID-19
Y Jin, H Yang, W Ji, W Wu, S Chen, W Zhang, G Duan - Viruses, 2020 - mdpi.com
The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
disease (COVID-19) in China has been brought to global attention and declared a pandemic …
disease (COVID-19) in China has been brought to global attention and declared a pandemic …
Natural product-derived phytochemicals as potential agents against coronaviruses: A review
Coronaviruses are responsible for a growing economic, social and mortality burden, as the
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …
How big data and artificial intelligence can help better manage the COVID-19 pandemic
SARS-CoV2 is a novel coronavirus, responsible for the COVID-19 pandemic declared by the
World Health Organization. Thanks to the latest advancements in the field of molecular and …
World Health Organization. Thanks to the latest advancements in the field of molecular and …
Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients
K Liu, Y Chen, R Lin, K Han - Journal of infection, 2020 - Elsevier
Background Due to the general susceptibility of new coronaviruses, the clinical
characteristics and outcomes of elderly and young patients may be different. Objective To …
characteristics and outcomes of elderly and young patients may be different. Objective To …
[HTML][HTML] Molecular docking, validation, dynamics simulations, and pharmacokinetic prediction of natural compounds against the SARS-CoV-2 main-protease
C Shivanika, D Kumar, V Ragunathan… - … structure & dynamics, 2020 - ncbi.nlm.nih.gov
The study aims to evaluate the potency of two hundred natural antiviral phytocompounds
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
Possible therapeutic effects of adjuvant quercetin supplementation against early-stage COVID-19 infection: a prospective, randomized, controlled, and open-label …
F Di Pierro, G Derosa, P Maffioli… - … journal of general …, 2021 - Taylor & Francis
Background Quercetin, a well-known naturally occurring polyphenol, has recently been
shown by molecular docking, in vitro and in vivo studies to be a possible anti-COVID-19 …
shown by molecular docking, in vitro and in vivo studies to be a possible anti-COVID-19 …
COVID-19 pandemic: epidemiology, etiology, conventional and non-conventional therapies
Coronavirus disease 2019 (COVID-19), which reported in an outbreak in 2019 in Wuhan,
Hubei province, China, is caused by the SARS-CoV-2 virus. The virus belongs to the beta …
Hubei province, China, is caused by the SARS-CoV-2 virus. The virus belongs to the beta …
[HTML][HTML] Application of big data technology for COVID-19 prevention and control in China: lessons and recommendations
J Wu, J Wang, S Nicholas, E Maitland, Q Fan - Journal of medical Internet …, 2020 - jmir.org
Background In the prevention and control of infectious diseases, previous research on the
application of big data technology has mainly focused on the early warning and early …
application of big data technology has mainly focused on the early warning and early …
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …
mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of …