Lennox-Gastaut syndrome: a comprehensive review

AA Asadi-Pooya - Neurological Sciences, 2018 - Springer
Lennox-Gastaut syndrome (LGS) is considered an epileptic encephalopathy and is defined
by a triad of multiple drug-resistant seizure types, a specific EEG pattern showing bursts of …

The epidemiology of the epilepsies in children

LD Cowan - Mental retardation and developmental disabilities …, 2002 - Wiley Online Library
The epilepsies are a heterogeneous collection of neurological conditions and syndromes
characterized by recurrent, unprovoked, paroxysmal seizure activity. There are several types …

ILAE classification and definition of epilepsy syndromes with onset in neonates and infants: Position statement by the ILAE Task Force on Nosology and Definitions

SM Zuberi, E Wirrell, E Yozawitz, JM Wilmshurst… - …, 2022 - Wiley Online Library
Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

[HTML][HTML] Effect of cannabidiol on drop seizures in the Lennox–Gastaut syndrome

O Devinsky, AD Patel, JH Cross… - … England Journal of …, 2018 - Mass Medical Soc
Background Cannabidiol has been used for treatment-resistant seizures in patients with
severe early-onset epilepsy. We investigated the efficacy and safety of cannabidiol added to …

DBS of thalamic centromedian nucleus for Lennox–Gastaut syndrome (ESTEL trial)

LJ Dalic, AEL Warren, KJ Bulluss… - Annals of …, 2022 - Wiley Online Library
Objective Prior uncontrolled studies have reported seizure reductions following deep brain
stimulation (DBS) in patients with Lennox–Gastaut syndrome (LGS), but evidence from …

[PDF][PDF] Role of brain inflammation in epileptogenesis

J Choi, S Koh - Yonsei medical journal, 2008 - synapse.koreamed.org
Inflammation is known to participate in the mediation of a growing number of acute and
chronic neurological disorders. Even so, the involvement of inflammation in the …

Epidemiology of epilepsy

C Behr, MA Goltzene, G Kosmalski, E Hirsch… - Revue neurologique, 2016 - Elsevier
Epilepsy is a burden affecting no fewer than 50 million patients worldwide. It is a
heterogeneous group of disorders comprising both common and very rare forms, thus …

Resting-state activity in development and maintenance of normal brain function

CE Pizoli, MN Shah, AZ Snyder… - Proceedings of the …, 2011 - National Acad Sciences
One of the most intriguing recent discoveries concerning brain function is that intrinsic
neuronal activity manifests as spontaneous fluctuations of the blood oxygen level …

[HTML][HTML] The burden of illness in Lennox–Gastaut syndrome: a systematic literature review

A Strzelczyk, SM Zuberi, P Striano, F Rosenow… - Orphanet Journal of …, 2023 - Springer
Abstract Background Lennox–Gastaut syndrome (LGS) is a severe developmental and
epileptic encephalopathy characterized by drug-resistant epilepsy with multiple seizure …

[HTML][HTML] The burden of pediatric status epilepticus: epidemiology, morbidity, mortality, and costs

K Gurcharran, ZM Grinspan - Seizure, 2019 - Elsevier
Purpose To summarize the epidemiology, morbidity, mortality, and costs of status epilepticus
(SE) in the pediatric population. Method Review of the medical literature. Results The overall …