Brown adipose tissue and novel management strategies for polycystic ovary syndrome therapy

Q Zhang, R Ye, YY Zhang, CC Fan, J Wang… - Frontiers in …, 2022 - frontiersin.org
Brown adipose tissue (BAT), a unique tissue, plays a key role in metabolism and energy
expenditure through adaptive nonshivering thermogenesis. It has recently become a …

Regulation of TRH neurons and energy homeostasis-related signals under stress

P Joseph-Bravo, L Jaimes-Hoy… - Journal of …, 2015 - joe.bioscientifica.com
Energy homeostasis relies on a concerted response of the nervous and endocrine systems
to signals evoked by intake, storage, and expenditure of fuels. Glucocorticoids (GCs) and …

MiR-494-3p regulates mitochondrial biogenesis and thermogenesis through PGC1-α signalling in beige adipocytes

M Lemecha, K Morino, T Imamura, H Iwasaki… - Scientific reports, 2018 - nature.com
Mitochondria are critical in heat generation in brown and beige adipocytes. Mitochondrial
number and function are regulated in response to external stimuli, such as cold exposure …

Characterization of cold‐induced remodelling reveals depot‐specific differences across and within brown and white adipose tissues in mice

R Jia, XQ Luo, G Wang, CX Lin, H Qiao… - Acta …, 2016 - Wiley Online Library
Aim Brown and beige adipose tissues dissipate energy in the form of heat via mitochondrial
uncoupling protein 1, defending against hypothermia and potentially obesity. The latter has …

[HTML][HTML] The effects of exercise and cold exposure on mitochondrial biogenesis in skeletal muscle and white adipose tissue

N Chung, J Park, K Lim - Journal of exercise nutrition & …, 2017 - ncbi.nlm.nih.gov
[Purpose] The purpose of this study was to determine whether exercise or/and cold
exposure regulate mitochondria biogenesis-related gene expression in soleus and inguinal …

Chronic ephedrine administration decreases brown adipose tissue activity in a randomised controlled human trial: implications for obesity

AL Carey, R Pajtak, MF Formosa, B Van Every… - Diabetologia, 2015 - Springer
Aims/hypothesis Brown adipose tissue (BAT) activation increases energy expenditure and
may have therapeutic potential to combat obesity. The primary activating and adaptive …

Translational pharmacology and physiology of brown adipose tissue in human disease and treatment

CJ Larson - Brown Adipose Tissue, 2019 - Springer
Human brown adipose tissue (BAT) is experimentally modeled to better understand the
biology of this important metabolic tissue, and also to enable the potential discovery and …

[HTML][HTML] Repeated short excursions from thermoneutrality suffice to restructure brown adipose tissue

VS Davies, E Lindsund, N Petrovic, B Cannon… - Biochimie, 2023 - Elsevier
Given the presence of brown adipose tissue in adult humans, an important issue is whether
human brown adipose tissue is recruitable. Cold exposure is the canonical recruitment …

The Effects of Intermittent Cold Exposure on Adipose Tissue

MC Scott, S Fuller - International Journal of Molecular Sciences, 2023 - mdpi.com
Intermittent cold exposure (ICE) has garnered increased attention in popular culture, largely
for its proposed effects on mood and immune function, but there are also suggestions that …

Effect of dexmedetomidine and cold stress in a rat model of neuropathic pain: Role of interleukin-6 and tumor necrosis factor-α

HSM Farghaly, AM Mahmoud… - European journal of …, 2016 - Elsevier
Dexmedetomidine (Dex) is a novel Alpha 2-adrenoceptor agonist. It decreases sympathetic
tone and attenuates the stress responses to anesthesia and surgery. People exposed to …