Opinion statement Colorectal cancer (CRC) is a major public health problem and the 2nd
leading-cause of cancer-related death worldwide. Around 30% of patients present with …

Background Stereotactic body radiotherapy (SBRT) is an emerging treatment option for liver
metastases in patients unsuitable for surgery. We investigated factors associated with …

Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of
death by cancer. Nearly 20% of patients with CRC will have metastases at the time of …

Many cancers can spread to the liver, often as the sole site of metastatic disease. For
properly selected patients with limited hepatic disease and good performance status, an …

Background: Treatment of advanced and metastatic colorectal cancer with irinotecan is
hampered by severe toxicities. The active metabolite of irinotecan, SN-38, is a known …

Chemotherapy resistance frequently drives tumor progression. However, the underlying
molecular mechanisms remain unclear. In this study, we found that the expression level of …

Risk factors for cancer-associated thrombosis are commonly divided into three categories:
patient-, cancer-, and treatment-related factors. Currently, different types of drugs are used in …

Background Over the last decade, multiple chemotherapies/targeted biologics have been
approved for metastatic colorectal cancer (mCRC). However, evidence is limited with …

Background Associating liver partition and portal vein ligation for staged hepatectomy
(ALPPS) has expanded and spearheaded development in hepatobiliary surgery …

The aim of the present study was to investigate the effect of hepatocyte growth factor
receptor (c‑Met) inhibition on the viability of colon cancer cells and xenografts exposed to …