Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Health benefits of quercetin in age-related diseases

Deepika, PK Maurya - Molecules, 2022 - mdpi.com
Polyphenols are the known group of phytochemicals that essentially consists of phenolic
rings. These are the plant product present in varied fruits and vegetables. These secondary …

[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism

Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Promising bioactive properties of quercetin for potential food applications and health benefits: A review

I Shabir, V Kumar Pandey, R Shams, AH Dar… - Frontiers in …, 2022 - frontiersin.org
Naturally occurring phytochemicals with promising biological properties are quercetin and
its derivatives. Quercetin has been thoroughly studied for its antidiabetic, antibacterial, anti …

Botanicals in postmenopausal osteoporosis

W Słupski, P Jawień, B Nowak - Nutrients, 2021 - mdpi.com
Osteoporosis is a systemic bone disease characterized by reduced bone mass and the
deterioration of bone microarchitecture leading to bone fragility and an increased risk of …

Emerging nano-scale delivery systems for the treatment of osteoporosis

AP Dayanandan, WJ Cho, H Kang, AB Bello… - Biomaterials …, 2023 - spj.science.org
Osteoporosis is a pathological condition characterized by an accelerated bone resorption
rate, resulting in decreased bone density and increased susceptibility to fractures …

Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N Xie, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Age related osteoporosis: targeting cellular senescence

U Föger-Samwald, K Kerschan-Schindl… - International journal of …, 2022 - mdpi.com
Age-related chronic diseases are an enormous burden to modern societies worldwide.
Among these, osteoporosis, a condition that predisposes individuals to an increased risk of …

[HTML][HTML] Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders

R Vlashi, X Zhang, M Wu, G Chen - Genes & Diseases, 2023 - Elsevier
Wnt signaling executes an indispensable performance in osteoblast differentiation, bone
development, homeostasis, and remodeling. Wnt signals trigger the intracellular Wnt …