Background Inflammation and stress response may be related to the occurrence of sepsis-
associated acute kidney injury (SA-AKI) in patients with sepsis. Insulin resistance (IR) is …

Introduction. The possible risk factors for chronic kidney disease in transplant recipients
have not been thoroughly investigated after living‐donor liver transplantation. Material and …

Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of
acute kidney injury of various origins, and may also promote progression from acute injury to …

Expansion of extracellular fluid volume with crystalloid solutions is a common medical
intervention, but its effects on renal cortical and medullary oxygenation are poorly …

Significance: Acute kidney injury (AKI) is a common and life-threatening complication in
hospitalized and critically ill patients. It is defined by an abrupt deterioration in renal function …

Background Sivelestat, a selective inhibitor of neutrophil elastase (NE), can mitigate sepsis-
related acute lung injury. However, the role of sivelestat in inhibiting oxidative stress and …

Background The mechanisms by which megadose sodium ascorbate improves clinical
status in experimental sepsis is unclear. We determined its effects on cerebral perfusion …

Sepsis, a life-threatening organ dysfunction, results from dysregulated host responses to
infection and still has a high incidence and mortality. Although administration of …

Purpose Urine oxygen partial pressure (PuO2) may be useful for assessing acute kidney
injury (AKI) risk. The primary purpose of this study was to quantify the ability of a novel …

Renal dysfunction is one of the most common complications of septic injury. One critical
contributor to septic injury-induced renal dysfunction is renal vascular dysfunction. Protein …