Alzheimer's disease (AD) is an age-related disease pathologically defined by the deposition
of amyloid plaques and neurofibrillary tangles in the brain parenchyma. Single-cell profiling …

The human brain is characterised by the most diverse morphological, metabolic and
functional structure among all body tissues. This is due to the existence of diverse neurons …

It is generally thought that under basal conditions, neurons produce ATP mainly through
mitochondrial oxidative phosphorylation (OXPHOS), and glycolytic activity only …

Neurons are particularly susceptible to energy fluctuations in response to stress.
Mitochondrial fission is highly regulated to generate ATP via oxidative phosphorylation; …

The unique morphology and functionality of central nervous system (CNS) neurons
necessitate specialized mechanisms to maintain energy metabolism throughout long axons …

Spinal cord injury (SCI) often leads to physical limitations, persistent pain, and major lifestyle
shifts, enhancing the likelihood of prolonged psychological stress and associated disorders …

In recent years, the role of mitochondrial dynamics in neurodegenerative diseases has
becoming increasingly important. More and more evidences have shown that in pathological …

Given their increasing industrial and biomedical applications, silver nanoparticles (AgNPs)
have become widely present in the environment. However, to date, studies on their potential …

Background The increasing prevalence of neurocognitive disorders (NCDs) in the aging
population worldwide has become a significant concern due to subjectivity of evaluations …

In Alzheimer's disease (AD), dysfunctional mitochondrial metabolism is associated with
synaptic loss, the major pathological correlate of cognitive decline. Mechanistic insight for …