Using circulating tumor DNA in colorectal cancer: current and evolving practices

M Malla, JM Loree, PM Kasi, AR Parikh - Journal of Clinical Oncology, 2022 - ascopubs.org
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …

Liquid biopsy in breast cancer: A comprehensive review

S Alimirzaie, M Bagherzadeh, MR Akbari - Clinical genetics, 2019 - Wiley Online Library
Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …

N6-methyladenine DNA modification in the human genome

CL Xiao, S Zhu, M He, D Chen, Q Zhang, Y Chen, G Yu… - Molecular cell, 2018 - cell.com
Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …

Recent advances and emerging trends in cancer biomarker detection technologies

RR Kumar, A Kumar, CH Chuang… - Industrial & Engineering …, 2023 - ACS Publications
Cancer is a major global health burden and poor survival rates can be attributed to lack of
early diagnosis and limited access to timely and standard treatments. Significant progress …

Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer

P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …

Tumor mutational burden standardization initiatives: recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy …

A Stenzinger, JD Allen, J Maas… - Genes …, 2019 - Wiley Online Library
Abstract Characterization of tumors utilizing next‐generation sequencing methods, including
assessment of the number of somatic mutations (tumor mutational burden [TMB]), is currently …

Profiling circulating tumour cells and other biomarkers of invasive cancers

M Poudineh, EH Sargent, K Pantel… - Nature Biomedical …, 2018 - nature.com
During cancer progression, many tumours shed circulating tumour cells (CTCs) and other
biomarkers into the bloodstream. The analysis of CTCs offers the prospect of collecting a …

Circulating tumor DNA as biomarkers for cancer detection

X Han, J Wang, Y Sun - Genomics, Proteomics and …, 2017 - academic.oup.com
Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …

[PDF][PDF] Liquid biopsy for cancer: circulating tumor cells, circulating free DNA or exosomes?

W Zhang, W Xia, Z Lv, C Ni, Y Xin, L Yang - Cellular Physiology and …, 2017 - karger.com
Precision medicine and personalized medicine are based on the development of
biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry …

Liquid biopsy in oral cancer

F Lousada-Fernandez, O Rapado-Gonzalez… - International journal of …, 2018 - mdpi.com
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a
complex process, in which heterogeneity plays an important role in the development and …