Using circulating tumor DNA in colorectal cancer: current and evolving practices
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …
Liquid biopsy in breast cancer: A comprehensive review
S Alimirzaie, M Bagherzadeh, MR Akbari - Clinical genetics, 2019 - Wiley Online Library
Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …
nature, effective breast cancer treatment can encounter many challenges. Traditional …
N6-methyladenine DNA modification in the human genome
Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …
Recent advances and emerging trends in cancer biomarker detection technologies
Cancer is a major global health burden and poor survival rates can be attributed to lack of
early diagnosis and limited access to timely and standard treatments. Significant progress …
early diagnosis and limited access to timely and standard treatments. Significant progress …
Liquid biopsies based on DNA methylation as biomarkers for the detection and prognosis of lung cancer
P Li, S Liu, L Du, G Mohseni, Y Zhang, C Wang - Clinical epigenetics, 2022 - Springer
Lung cancer (LC) is the main cause of cancer-related mortality. Most LC patients are
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …
diagnosed in an advanced stage when the symptoms are obvious, and the prognosis is …
Tumor mutational burden standardization initiatives: recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy …
A Stenzinger, JD Allen, J Maas… - Genes …, 2019 - Wiley Online Library
Abstract Characterization of tumors utilizing next‐generation sequencing methods, including
assessment of the number of somatic mutations (tumor mutational burden [TMB]), is currently …
assessment of the number of somatic mutations (tumor mutational burden [TMB]), is currently …
Profiling circulating tumour cells and other biomarkers of invasive cancers
During cancer progression, many tumours shed circulating tumour cells (CTCs) and other
biomarkers into the bloodstream. The analysis of CTCs offers the prospect of collecting a …
biomarkers into the bloodstream. The analysis of CTCs offers the prospect of collecting a …
Circulating tumor DNA as biomarkers for cancer detection
X Han, J Wang, Y Sun - Genomics, Proteomics and …, 2017 - academic.oup.com
Detection of circulating tumor DNAs (ctDNAs) in cancer patients is an important component
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …
of cancer precision medicine ctDNAs. Compared to the traditional physical and biochemical …
[PDF][PDF] Liquid biopsy for cancer: circulating tumor cells, circulating free DNA or exosomes?
Precision medicine and personalized medicine are based on the development of
biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry …
biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry …
Liquid biopsy in oral cancer
F Lousada-Fernandez, O Rapado-Gonzalez… - International journal of …, 2018 - mdpi.com
Oral cancer is one of the most prevalent forms of cancer worldwide. Carcinogenesis is a
complex process, in which heterogeneity plays an important role in the development and …
complex process, in which heterogeneity plays an important role in the development and …