Pathogenesis of cancers derived from thyroid follicular cells

JA Fagin, GP Krishnamoorthy, I Landa - Nature reviews Cancer, 2023 - nature.com
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …

[PDF][PDF] Management of thyroid nodules

M Uludag, MT Unlu, M Kostek, N Aygun… - … Medical Bulletin of …, 2023 - jag.journalagent.com
Thyroid nodules are common and the prevalence varies between 4 and 7% by palpation
and 19–68% by high-resolution USG. Most thyroid nodules are benign, and the malignancy …

Thyroid carcinoma: a review for 25 years of environmental risk factors studies

E Kruger, EA Toraih, MH Hussein, SA Shehata… - Cancers, 2022 - mdpi.com
Simple Summary Increasing awareness of thyroid cancer-related environmental risk factors
is considered an essential tool for cancer prevention through risk prevention/management …

Identification of a Novel Germline PPP4R3A Missense Mutation Asp409Asn on Familial Non-Medullary Thyroid Carcinoma

Y Hu, Z Han, H Guo, N Zhang, N Shen, Y Jiang… - Biomedicines, 2024 - mdpi.com
Familial non-medullary thyroid carcinoma (FNMTC) accounts for 3% to 9% of all thyroid
cancer cases, yet its genetic mechanisms remain unknown. Our study aimed to screen and …

Cancer Predisposition Syndromes and Thyroid Cancer: Keys for a Short Two-Way Street

I Balinisteanu, MC Panzaru, L Caba, MC Ungureanu… - Biomedicines, 2023 - mdpi.com
Cancer predisposition syndromes are entities determined especially by germinal pathogenic
variants, with most of them autosomal dominantly inherited. The risk of a form of cancer is …

Paediatric differentiated thyroid carcinoma: a UK national clinical practice consensus guideline

SR Howard, S Freeston, B Harrison… - Endocrine-Related …, 2022 - erc.bioscientifica.com
This guideline is written as a reference document for clinicians presented with the challenge
of managing paediatric patients with differentiated thyroid carcinoma up to the age of 19 …

Novel susceptibility genes drive familial non-medullary thyroid cancer in a large consanguineous kindred

P Majdalani, U Yoel, T Nasasra, M Fraenkel… - International Journal of …, 2023 - mdpi.com
Familial non-medullary thyroid cancer (FNMTC) is a well-differentiated thyroid cancer (DTC)
of follicular cell origin in two or more first-degree relatives. Patients typically demonstrate an …

CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function

C Pires, IJ Marques, M Valério, A Saramago… - Journal of Biological …, 2024 - ASBMB
Approximately 5 to 15% of nonmedullary thyroid cancers (NMTC) present in a familial form
(familial nonmedullary thyroid cancers [FNMTC]). The genetic basis of FNMTC remains …

[HTML][HTML] 112 Differentiated Thyroid Cancer with Synchronous second Primary Cancer: Retrospective study from a cancer institute in India

A Chowdhury, J Aaron, A Bandi, P Rathod - Radiotherapy and Oncology, 2024 - Elsevier
Purpose/Objective Thyroid cancer is the most common endocrine malignancy, accounting
for 1% of all cancers 1. The genetic syndromes associated with differentiated thyroid cancers …

Diagnose und Therapie von Schilddrüsenkrebs

S Schüle, A Darr, A Anneken, T Hahn - MMW-Fortschritte der Medizin, 2023 - Springer
Schilddrüsenkarzinome zählen mit einer jährlichen Inzidenz von 4, 1/100.000 Frauen und 1,
5/100.000 Männern zu den seltenen Krebserkrankungen und treten oft bereits im mittleren …