The overall 5‐year relative survival rate for all cancers combined is now 68%, and there are
over 16.9 million survivors in the United States. Evidence from laboratory and observational …

A few decades have passed since intensive care unit (ICU) beds have been available for
critically ill patients with cancer. Although the initial reports showed dismal prognosis, recent …

Background Patients with cancer have been shown to have a higher risk of clinical severity
and mortality compared to non-cancer patients with COVID-19. Patients with hematologic …

Background Leukaemia is a heterogeneous group of haemopoietic cancers that comprises
a number of diverse and biologically distinct subgroups. We examine the leukaemia burden …

Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice,
With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of …

Abstract Background Hematologic malignancies (HMs) are a heterogeneous group of
cancers that comprise diverse subgroups of neoplasms. So far, despite the major …

1Department of Haematology, Queen Elizabeth Hospital, Birmingham, 2Department of
Clinical Oncology, Christie Hospital, Manchester, 3PET Imaging Centre, King's College …

Hematological malignancies (HM) are a collection of malignant transformations originating
from cells in the primary or secondary lymphoid organs. Leukemia, lymphoma, and multiple …

Background Leukaemias comprise a heterogenous group of haematological malignancies.
In CONCORD-3, we analysed data for children (aged 0–14 years) and adults (aged 15–99 …

The hypoxic microenvironment is an essential characteristic of most malignant tumors.
Notably, hypoxia-inducible factor-1 alpha (HIF-1α) is a key regulatory factor of cellular …