Safety evaluation of an Ayurvedic medicine, Arogyavardhini vati on brain, liver and kidney in rats

G Kumar, A Srivastava, SK Sharma… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Arogyavardhini vati, an Ayurvedic polyherbal
formulation has been used for liver and skin disorders in the Ayurvedic system of medicine …

Methylmercury neurotoxicity: Role of oxidative stress

AM Reardon, HK Bhat - Toxicological & Environmental Chemistry, 2007 - Taylor & Francis
Methylmercury (MeHg) is a highly toxic compound that successfully traverses the blood
brain barrier with deleterious effects to the central nervous system. Exposure is generally …

Ascorbic acid protects against anxiogenic-like effect induced by methylmercury in zebrafish: action on the serotonergic system

B Puty, C Maximino, A Brasil, WLL da Silva… - Zebrafish, 2014 - liebertpub.com
To evaluate the protector effect of ascorbic acid (AA) against anxiogenic-like effect induced
by methylmercury (MeHg) exposure, adult zebrafish were treated with AA (2 mg g− 1 …

Safety evaluation of mercury based Ayurvedic formulation (Sidh Makardhwaj) on brain cerebrum, liver & kidney in rats

G Kumar, A Srivastava, SK Sharma… - Indian Journal of …, 2014 - journals.lww.com
Methods: Graded doses of SM (10, 50, 100 mg/kg), mercuric chloride (1 mg/kg) and normal
saline were administered orally to male Wistar rats for 28 days. Behavioural parameters …

[HTML][HTML] Effect of low-level prenatal mercury exposure on neonate neurobehavioral development in China

J Wu, T Ying, Z Shen, H Wang - Pediatric neurology, 2014 - Elsevier
Background This study aimed to assess the effects of low-level prenatal mercury exposure
on neonate neurobehavioral development in China. Methods In total, 418 mother-neonate …

Assessment of sub-chronic oral toxicity of Nityanand Rasa: an ayurvedic herbo-metallic formulation

SR Kshirsagar, M Kumari, SM Bajad… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Nityananda Rasa (NR) is an ayurvedic herbo-
metallic formulation used to treat gout, obesity, hypothyroidism, elephantiasis, and other …

[HTML][HTML] Dietary choline deprivation impairs rat brain mitochondrial function and behavioral phenotype

C Pacelli, A Coluccia, I Grattagliano, T Cocco… - The Journal of …, 2010 - Elsevier
Dietary choline deprivation (CD) is associated with behavioral changes, but mechanisms
underlying these detrimental effects are not well characterized. For instance, no literature …

Low level methylmercury enhances CNTF-evoked STAT3 signaling and glial differentiation in cultured cortical progenitor cells

NJ Jebbett, JW Hamilton, MD Rand, F Eckenstein - Neurotoxicology, 2013 - Elsevier
Although many previous investigations have studied how mercury compounds cause cell
death, sub-cytotoxic levels may affect mechanisms essential for the proper development of …

Unravelling motor behaviour hallmarks in intoxicated adolescents: methylmercury subtoxic-dose exposure and binge ethanol intake paradigm in rats

AN Oliveira, AM Pinheiro, IJA Belém-Filho… - … Science and Pollution …, 2018 - Springer
Methylmercury (MeHg) is a hazardous environmental pollutant, affecting Amazon basin
communities by anthropogenic activities. The exact safe level of MeHg exposure is unclear …

Neurobehavioral effect of chronic and bolus doses of methylmercury following prenatal exposure in C57BL/6 weanling mice

J Liang, M Inskip, D Newhook, C Messier - Neurotoxicology and teratology, 2009 - Elsevier
Several studies with animals have shown that even low and medium prenatal and postnatal
exposure to methylmercury (MeHg) can result in locomotor, motor coordination and learning …