Short-chain fatty acids (SCFAs) are carboxylic acids produced as a result of gut microbial
anaerobic fermentation. They activate signaling cascades, acting as ligands of G-protein …

ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …

The intestinal barrier is complex and consists of multiple layers, and it provides a physical
and functional barrier to the transport of luminal contents to systemic circulation. While the …

The gastrointestinal tract is coated by a thick layer of mucus that forms the front line of innate
host defense. Mucus consists of high molecular weight glycoproteins called mucins that are …

Background & Aims Food additives, such as emulsifiers, stabilizers, or bulking agents, are
present in the Western diet and their consumption is increasing. However, little is known …

The disruption of the protective intestinal barrier—the 'leaky gut'—is a common complication
of the inflammatory bowel disease. There is limited data on the mechanisms of the intestinal …

The gastrointestinal barrier is-with approximately 400 m 2-the human body's largest surface
separating the external environment from the internal milieu. This barrier serves a dual …

The mucus layer is the first line of innate host defense in the gut that protects the epithelium
by spatially separating commensal bacteria. MUC2 mucin is produced and stored by goblet …

Entamoeba histolytica is the third-leading cause of parasitic mortality globally. E. histolytica
infection generally does not cause symptoms, but the parasite has potent pathogenic …

MUC2 mucin is the major glycoprotein in colonic mucus that separates intestinal microbiota
from underlying host cells and serves as a food source for some eubacteria. MUC2 …