AGE/RAGE signaling has been a well‐studied cascade in many different disease states,
particularly diabetes. Due to the complex nature of the receptor and multiple intersecting …

Fetuin-A is a heterodimeric plasma glycoprotein containing an A-chain of 282 amino acids
and a B-chain of 27 amino acid residues linked by a single inter-disulfide bond. It is …

Metabolic syndrome and its components are associated with chronic kidney disease (CKD)
development. Insulin resistance (IR) plays a central role in the metabolic syndrome and is …

The prevalence of type 2 diabetes is increasing globally and poses a heavy burden on
public health and socioeconomic development of all nations. Type 2 diabetes is a …

Background & Aims Prolactin (PRL) is a multifunctional polypeptide with effects on
metabolism, however, little is known about its effect on hepatic steatosis and lipid …

Abstract Fetuin-A (Alfa 2-Heremans-Schmid) is a glycoprotein that is mainly synthesized by
hepatocytes and then released into the bloodstream. While fetuin-A, a multifunctional …

Abstract Purpose of Review Chronic inflammation, adipokines, and hepatokines have been
identified as basis of insulin resistance and β cell failure in animal models. We present our …

This review examines the potential relationship between serum inflammation markers and
type 2 diabetes mellitus (T2DM). Inflammation markers have been proposed as prognostic …

Hepatokines (liver secreted proteins with possible distant action) are emerging potential
players in insulin resistance in type 2 diabetic patients. Here, we explored the effect of a high …

Aims Fetuin-A has been linked to insulin resistance and obesity. Its role in the pathogenesis
of type 2 diabetes (T2DM) has also been discussed. We aimed to investigate the prospective …