Leuprorelin (leuprolide acetate) is a gonadotrophin-releasing hormone (GnRH) analogue
used to treat a wide range of sex hormone-related disorders including advanced prostatic …

Background Standard androgen suppression therapy (AST) using surgical or medical
castration is considered a mainstay of advanced hormone‐sensitive prostate cancer …

Synopsis Leuprorelin (leuprolide acetate) is a synthetic analogue of gonadotrophin-
releasing hormone (GnRH)[luteinising hormone-releasing hormone (LHRH)] which initially …

Prostatic metastases in the nose and paranasal sinsuses are rare. Seven cases have
previously been reported in the world literature. We describe the clinical presentation of a …

Many patients with prostate cancer present with ad vanced disease (stage C or D). For these
patients, treatment is palliative and is aimed at reducing serum testosterone levels. Since the …

A high proportion of prostate cancer has been shown to be hormone-dependent, in
particular, dependent on testosterone (T) and dihydrotestosterone (OHT). The biosynthesis …