Liver cirrhosis contributes to the disorder of gut microbiota in patients with hepatocellular carcinoma

R Zheng, G Wang, Z Pang, N Ran, Y Gu… - Cancer …, 2020 - Wiley Online Library
Background Gut microbiota (GM) of patients with liver cancer is disordered, and syet no
study reported the GM distribution of liver cirrhosis‐induced HCC (LC‐HCC) and nonliver …

EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model

X Tao, R Zhang, R Du, T Yu, H Yang, J Li… - Journal of Experimental …, 2022 - rupress.org
Natural killer (NK) cells exhibit antifibrotic properties in liver fibrosis (LF) by suppressing
activated hepatic stellate cell (HSC) populations. Prostaglandin E2 (PGE2) plays a dual role …

[HTML][HTML] Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps …

Y Liu, X Zhang, S Chen, J Wang, S Yu, Y Li… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Methods Serum samples from both binge drinking and alcohol-avoiding patients were
analyzed. Mouse models of chronic plus binge alcohol-induced hepatosteatosis and HCC …

[HTML][HTML] Silymarin for treating toxic liver disease: international consensus recommendations

A Gillessen, F Angelico, J Chen, L Lu, MI Lucena… - Gastro Hep …, 2022 - Elsevier
Chronic liver disease (CLD) is a leading health problem impacting the quality of life globally.
China shares a major global burden of CLD—including alcoholic liver disease, nonalcoholic …

[HTML][HTML] CD73-Adenosine A1R Axis Regulates the Activation and Apoptosis of Hepatic Stellate Cells Through the PLC-IP3-Ca2+/DAG-PKC Signaling Pathway

Z Liu, X Wu, Q Wang, Z Li, X Liu, X Sheng… - Frontiers in …, 2022 - frontiersin.org
Alcohol-related liver fibrosis (ALF) is a form of alcohol-related liver disease (ALD) that
generally occurs in response to heavy long-term drinking. Ecto-5′-nucleotidase (NT5E) …

[HTML][HTML] Alcoholic Liver Disease in China: A Disease Influenced by Complex Social Factors That Should Not Be Neglected

X Feng, N Huang, Y Wu, F Gao, X Chen… - Journal of Clinical …, 2024 - xiahepublishing.com
Alcoholic liver disease (ALD) encompasses liver damage caused by chronic, excessive
alcohol consumption. It manifests initially as marked hepatocellular steatosis and can …

[HTML][HTML] Development and validation of an online dynamic nomogram based on the atherogenic index of plasma to screen nonalcoholic fatty liver disease

H Peng, J Zhang, X Huang, M Xu, J Huang… - Lipids in Health and …, 2023 - Springer
Background Nonalcoholic fatty liver disease (NAFLD), a common liver disease worldwide,
can be reversed early in life with lifestyle and medical interventions. This study aimed to …

[HTML][HTML] Derivation and validation of a nomogram for predicting 90-day survival in patients with HBV-related acute-on-chronic liver failure

J Chen, W Weng, M Huang, X Peng, J He… - Frontiers in …, 2021 - frontiersin.org
Background: Conventional prognostic models do not fully reflect the severity of hepatitis B
virus (HBV)-related acute-on-chronic liver failure (ACLF). This study aimed to establish an …

[HTML][HTML] The composite risk index based on frailty predicts postoperative complications in older patients recovering from elective digestive tract surgery: a retrospective …

CQ Li, C Zhang, F Yu, XY Li, DX Wang - BMC anesthesiology, 2022 - Springer
Background Limitations exist in available studies investigating effect of preoperative frailty
on postoperative outcomes. This study was designed to analyze the association between …

Quantitative Profiling of Oxylipin Reveals the Mechanism of Pien‐Tze‐Huang on Alcoholic Liver Disease

Z Zhu, W Zhou, Y Yang, K Wang, F Li… - Evidence‐Based …, 2021 - Wiley Online Library
Alcoholic liver disease (ALD) is a liver disease caused by long‐term alcohol consumption.
ROS‐mediated oxidative stress is the leading cause of ALD. Pien‐Tze‐Huang (PZH), a …