BACKGROUND Advanced maternal age is associated with decreased oocyte quantity and
quality as well as uterine and placental dysfunctions. These changes lead to infertility …

Uterine aging is an important factor that impacts fertility, reproductive health, and uterus-
related diseases; however, it remains poorly explored. Functionally, these disturbances …

Mammalian reproductive performance declines rapidly with advanced maternal age. This
effect is largely attributed to the exponential increase in chromosome segregation errors in …

The uterine fibrosis contributes to gestational outcomes. Collagen deposition in the uterus is
related to uterine aging. Senolytic therapies are an option for reducing health complications …

The prevalence of cardiovascular disease has increased among middle-aged women in the
United States, yet has declined in middle-aged men. In experimental stroke, middle-aged …

Weaning marks an important milestone during life history in mammals indicating nutritional
independence from the mother. Age at weaning is a key measure of maternal investment …

Key points Older pregnant women have a greater risk of operative delivery, still birth and
post‐term induction. This suggests that maternal age can influence the timing of birth and …

Aims: The study aimed to evaluate the effects of pretreated Chinese herbal medicine
(PCHM) on egg quality, production performance, histopathological changes in the uterus …

Objective The effects of alpha lipoic acid (ALA) and its possible mechanisms in treating
Primary ovarian failure (POF) model was studied with 4 vinylcyclohexene diepoxide (VCD) …

Abstract d‐galactose (DG)‐induced rodent aging model has widely been used for the study
of age‐related dysfunctions of various organs, including gonads and uterus. Antidiabetic …