[HTML][HTML] TERT—regulation and roles in cancer formation

M Dratwa, B Wysoczańska, P Łacina, T Kubik… - Frontiers in …, 2020 - frontiersin.org
Telomerase reverse transcriptase (TERT) is a catalytic subunit of telomerase. Telomerase
complex plays a key role in cancer formation by telomere dependent or independent …

Biologic and clinical perspectives on thyroid cancer

JA Fagin, SA Wells Jr - New England Journal of Medicine, 2016 - Mass Medical Soc
Biologic and Clinical Perspectives on Thyroid Cancer | NEJM Skip to main content NEJM
Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

[HTML][HTML] Thyroidectomy without radioiodine in patients with low-risk thyroid cancer

S Leboulleux, C Bournaud, CN Chougnet… - … England Journal of …, 2022 - Mass Medical Soc
Background In patients with low-risk differentiated thyroid cancer undergoing thyroidectomy,
the postoperative administration of radioiodine (iodine-131) is controversial in the absence …

The American Association of Endocrine Surgeons guidelines for the definitive surgical management of thyroid disease in adults

KN Patel, L Yip, CC Lubitz, EG Grubbs, BS Miller… - Annals of …, 2020 - journals.lww.com
Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

[HTML][HTML] Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer

R Leão, JD Apolónio, D Lee, A Figueiredo… - Journal of biomedical …, 2018 - Springer
Background Limitless self-renewal is one of the hallmarks of cancer and is attained by
telomere maintenance, essentially through telomerase (h TERT) activation. Transcriptional …

[HTML][HTML] Papillary thyroid cancer prognosis: An evolving field

S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …

Thyroid cancer

ME Cabanillas, DG McFadden, C Durante - The Lancet, 2016 - thelancet.com
Thyroid cancer is the fifth most common cancer in women in the USA, and an estimated over
62 000 new cases occurred in men and women in 2015. The incidence continues to rise …

Mortality risk stratification by combining BRAF V600E and TERT promoter mutations in papillary thyroid cancer: genetic duet of BRAF and TERT promoter mutations in …

R Liu, J Bishop, G Zhu, T Zhang, PW Ladenson… - JAMA …, 2017 - jamanetwork.com
Importance BRAF V600E andTERTpromoter mutations can coexist in papillary thyroid
cancer (PTC). This genetic duet was indicated to be involved in the aggressiveness of PTC …

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

NTRK fusion oncogenes in pediatric papillary thyroid carcinoma in northeast United States

ML Prasad, M Vyas, MJ Horne, RK Virk, R Morotti… - Cancer, 2016 - Wiley Online Library
BACKGROUND An increase in thyroid cancers, predominantly papillary thyroid carcinoma
(PTC), has been recently reported in children. METHODS The histopathology of 28 …