Type 1 and type 2 diabetes are characterized by chronic inflammation; both diseases
involve pancreatic islet inflammation, while systemic low-grade inflammation is a feature of …

Psychological stress is common in many physical illnesses and is increasingly recognized
as a risk factor for disease onset and progression. An emerging body of literature suggests …

The role of inflammation in the pathogenesis of type 2 diabetes and associated
complications is now well established. Several conditions that are driven by inflammatory …

Components of the immune system are altered in obesity and type 2 diabetes (T2D), with the
most apparent changes occurring in adipose tissue, the liver, pancreatic islets, the …

Type 2 diabetes mellitus (T2DM) is characterized by progressive β‐cell dysfunctioning and
insulin resistance. This article reviews recent literature with special focus on inflammatory …

The increasing prevalence, variable pathogenesis, progressive natural history, and
complications of type 2 diabetes emphasise the urgent need for new treatment strategies …

The role of the immune system is to restore functionality in response to stress. Increasing
evidence shows that this function is not limited to insults by infection or injury and plays a …

Onset of Type 2 diabetes occurs when the pancreatic β-cell fails to adapt to the increased
insulin demand caused by insulin resistance. Morphological and therapeutic intervention …

Both common forms of diabetes have an inflammatory pathogenesis in which immune and
metabolic factors converge on interleukin-1β as a key mediator of insulin resistance and β …

Islets produce a variety of cytokines and chemokines in response to physiologic and
pathologic stimulation by nutrients. The cellular source of these inflammatory mediators …