SERRATE: a key factor in coordinated RNA processing in plants

M Jozwiak, D Bielewicz, Z Szweykowska-Kulinska… - Trends in Plant …, 2023 - cell.com
The SERRATE (SE) protein is involved in the processing of RNA polymerase II (RNAPII)
transcripts. It is associated with different complexes engaged in different aspects of plant …

How structural features define biogenesis and function of human telomerase RNA primary transcript

M Rubtsova, O Dontsova - Biomedicines, 2022 - mdpi.com
Telomerase RNA has been uncovered as a component of the telomerase enzyme, which
acts as a reverse transcriptase and maintains the length of telomeres in proliferated …

SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis

M Bajczyk, H Lange, D Bielewicz, L Szewc… - Nucleic Acids …, 2020 - academic.oup.com
SERRATE/ARS2 is a conserved RNA effector protein involved in transcription, processing
and export of different types of RNAs. In Arabidopsis, the best-studied function of SERRATE …

The U1 snRNP subunit LUC7 modulates plant development and stress responses via regulation of alternative splicing

M de Francisco Amorim, EM Willing, EX Szabo… - The Plant …, 2018 - academic.oup.com
Introns are removed by the spliceosome, a large macromolecular complex composed of five
ribonucleoprotein subcomplexes (U snRNPs). The U1 snRNP, which binds to 5ʹ splice …

Mapping domains of ARS2 critical for its RNA decay capacity

M Melko, K Winczura, JO Rouvière… - Nucleic Acids …, 2020 - academic.oup.com
ARS2 is a conserved protein centrally involved in both nuclear RNA productive and
destructive processes. To map features of ARS2 promoting RNA decay, we utilized two …

Catalytic activities, molecular connections, and biological functions of plant RNA exosome complexes

H Lange, D Gagliardi - The Plant Cell, 2022 - academic.oup.com
RNA exosome complexes provide the main 3′–5′-exoribonuclease activities in eukaryotic
cells and contribute to the maturation and degradation of virtually all types of RNA. RNA …

ARS2 is required for retinal progenitor cell S-phase progression and Müller glial cell fate specification

C O'Sullivan, PEB Nickerson, O Krupke… - … and Cell Biology, 2020 - cdnsciencepub.com
During a developmental period that extends postnatally in the mouse, proliferating
multipotent retinal progenitor cells produce one of 7 major cell types (rod, cone, bipolar …

ARS2 Plays Diverse Roles in DNA Damage Response, Fungal Development, and Pathogenesis in the Plant Pathogenic Fungus Fusarium graminearum

DC Bui, JE Kim, J Shin, JY Lim, GJ Choi… - Frontiers in …, 2019 - frontiersin.org
Arsenite-resistance protein 2 (Ars2) is an important nuclear protein involved in various RNA
metabolisms in animals and plants, but no Ars2 ortholog has been studied in filamentous …

Cytoplasmic switch of ARS2 isoforms promotes nonsense-mediated mRNA decay and arsenic sensitivity

MM Perez - 2022 - dspace.library.uvic.ca
The life of RNA polymerase II (RNAPII) transcripts is shaped by the dynamic formation of
mutually exclusive ribonucleoprotein complexes (RNPs) that direct transcript biogenesis and …

The U1 snRNP subunit LUC7 controls plant development and stress response through alternative splicing regulation

MF Amorim, EM Willing, AG Francisco-Mangilet… - bioRxiv, 2017 - biorxiv.org
Introns are removed by the spliceosome, a large macromolecular complex composed of five
ribonucleoprotein subcomplexes (U snRNP). The U1 snRNP, which binds to 5'splice sites …