Simple Summary Major progress has been achieved in stage-IV bone metastatic patients to
control over the disease progression, thereby resulting in longer survival. Self-autonomy and …

Introduction Pathologic vertebral fractures are a major clinical concern in the management of
cancer patients with metastatic spine disease. These fractures are a direct consequence of …

Spine is the most common site for bone metastases. The evaluation of the mechanical
competence and failure location in metastatic vertebrae is a biomechanical and clinical …

Metastatic bone disease occurs in 70–80% of advanced breast cancer patients and bone
tissue is accepted to have attractive physical properties that facilitate cancer cell attraction …

The structural performance of a vertebra can be significantly undermined if it develops a
tumour, that could even lead to the vertebra's structural collapse. In cancers with a high …

The evaluation of the local mechanical behavior as a result of metastatic lesions is
fundamental for the characterization of the mechanical competence of metastatic vertebrae …

Background Bone metastases may lead to spine instability and increase the risk of fracture.
Scoring systems are available to assess critical metastases, but they lack specificity, and …

The spine is the first site for incidence of bone metastasis. Thus, the vertebrae have a high
potential risk of being weakened by metastatic tissues. The evaluation of strength of the …

Human prostatic tissue exhibits complex mechanical behaviour due to its multiphasic,
heterogeneous nature, with hierarchical microstructures involving epithelial compartments …

Introduction: Measurement uncertainties of Digital Volume Correlation (DVC) are influenced
by several factors, like input images quality, correlation algorithm, bone type, etc. However, it …