Blood‐brain barrier overview: structural and functional correlation
A Alahmari - Neural plasticity, 2021 - Wiley Online Library
The blood‐brain barrier (BBB) is a semipermeable and extremely selective system in the
central nervous system of most vertebrates, that separates blood from the brain's …
central nervous system of most vertebrates, that separates blood from the brain's …
[HTML][HTML] CAR T cell-based immunotherapy for the treatment of glioblastoma
Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumor in adults. Current treatment options typically consist of surgery followed by …
tumor in adults. Current treatment options typically consist of surgery followed by …
Reviewing the significance of blood–brain barrier disruption in multiple sclerosis pathology and treatment
The disruption of blood–brain barrier (BBB) for multiple sclerosis (MS) pathogenesis has a
double effect: early on during the onset of the immune attack and later for the CNS self …
double effect: early on during the onset of the immune attack and later for the CNS self …
Neuroinflammation: the role and consequences
M Lyman, DG Lloyd, X Ji, MP Vizcaychipi, D Ma - Neuroscience research, 2014 - Elsevier
Neuroinflammation is central to the common pathology of several acute and chronic brain
diseases. This review examines the consequences of excessive and prolonged …
diseases. This review examines the consequences of excessive and prolonged …
Targeting neuroinflammation in Alzheimer's disease
MR Bronzuoli, A Iacomino, L Steardo… - Journal of inflammation …, 2016 - Taylor & Francis
Almost 47 million people suffer from dementia worldwide, with an estimated new case
diagnosed every 3.2 seconds. Alzheimer's disease (AD) accounts for approximately 60 …
diagnosed every 3.2 seconds. Alzheimer's disease (AD) accounts for approximately 60 …
Inflammatory cell trafficking across the blood–brain barrier: chemokine regulation and in vitro models
Y Takeshita, RM Ransohoff - Immunological reviews, 2012 - Wiley Online Library
The blood–brain barrier (BBB) is the brain‐specific capillary barrier that is critical for
preventing toxic substances from entering the central nervous system (CNS). In contrast to …
preventing toxic substances from entering the central nervous system (CNS). In contrast to …
T‐cell trafficking in the central nervous system
F Sallusto, D Impellizzieri, C Basso… - Immunological …, 2012 - Wiley Online Library
To perform their distinct effector functions, pathogen‐specific T cells have to migrate to target
tissue where they recognize antigens and produce cytokines that elicit appropriate types of …
tissue where they recognize antigens and produce cytokines that elicit appropriate types of …
CNS: Not an immunoprivilaged site anymore but a virtual secondary lymphoid organ
N Negi, BK Das - International reviews of immunology, 2018 - Taylor & Francis
The cardinal dogma of central nervous system (CNS) immunology believed brain is an
immune privileged site, but scientific evidences gathered so far have overturned this notion …
immune privileged site, but scientific evidences gathered so far have overturned this notion …
Biology of the blood–nerve barrier and its alteration in immune mediated neuropathies
T Kanda - Journal of Neurology, Neurosurgery & Psychiatry, 2013 - jnnp.bmj.com
The blood–nerve barrier (BNB) is a dynamic and competent interface between the
endoneurial microenvironment and the surrounding extracellular space or blood. It is …
endoneurial microenvironment and the surrounding extracellular space or blood. It is …
Molecular anti-inflammatory mechanisms of retinoids and carotenoids in Alzheimer's disease: A review of current evidence
N Mohammadzadeh Honarvar… - Journal of Molecular …, 2017 - Springer
Alzheimer's disease (AD) is considered as one of the most prevalent neurodegenerative
disorders characterized by progressive loss of mental function and ability to learn. AD is a …
disorders characterized by progressive loss of mental function and ability to learn. AD is a …