[HTML][HTML] Clinical translation of silica nanoparticles

TI Janjua, Y Cao, C Yu, A Popat - Nature Reviews Materials, 2021 - nature.com
Silica nanoparticles have entered clinical trials for a variety of biomedical applications,
including oral drug delivery, diagnostics, plasmonic resonance and photothermal ablation …

Recent applications of immunomodulatory biomaterials for disease immunotherapy

H Dai, Q Fan, C Wang - Exploration, 2022 - Wiley Online Library
Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …

Poly(l‐Histidine)‐Mediated On‐Demand Therapeutic Delivery of Roughened Ceria Nanocages for Treatment of Chemical Eye Injury

CJ Yang, DD Nguyen, JY Lai - Advanced Science, 2023 - Wiley Online Library
Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …

[HTML][HTML] Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Recent progress of magnetic nanoparticles in biomedical applications: A review

MI Anik, MK Hossain, I Hossain, A Mahfuz… - Nano …, 2021 - Wiley Online Library
Magnetic nanoparticles (MNPs) offer tremendous potentialities in biomedical applications for
a long while. Since these materials' interactions in biological media largely rely on their …

[HTML][HTML] Engineering nanoparticle toolkits for mRNA delivery

B Sun, W Wu, EA Narasipura, Y Ma, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

Bioinspired Spatiotemporal Management toward RNA Therapies

Y Ma, S Li, X Lin, Y Chen - ACS nano, 2023 - ACS Publications
Ribonucleic acid (RNA)-based therapies have become an attractive topic in disease
intervention, especially with some that have been approved by the FDA such as the mRNA …

Advances and future perspectives in epithelial drug delivery

Y Mohammed, A Holmes, PCL Kwok, T Kumeria… - Advanced Drug Delivery …, 2022 - Elsevier
Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …

Advances in mRNA therapeutics for cancer immunotherapy: from modification to delivery

G Han, D Noh, H Lee, S Lee, S Kim, HY Yoon… - Advanced Drug Delivery …, 2023 - Elsevier
RNA vaccines have demonstrated their ability to solve the issues posed by the COVID-19
pandemic. This success has led to the renaissance of research into mRNA and their …