Histone deacetylases as new therapeutic targets in triple-negative breast cancer: Progress and promises
N Garmpis, C Damaskos, A Garmpi… - Cancer Genomics & …, 2017 - cgp.iiarjournals.org
Triple-negative breast cancer (TNBC) lacks expression of estrogen receptor (ER),
progesterone receptor (PR) and HER2 gene. It comprises approximately 15-20% of breast …
progesterone receptor (PR) and HER2 gene. It comprises approximately 15-20% of breast …
Role of growth hormone in breast cancer
Breast cancer is one of the most common cancers diagnosed in women. Approximately two-
thirds of all breast cancers diagnosed are classified as hormone dependent, which indicates …
thirds of all breast cancers diagnosed are classified as hormone dependent, which indicates …
Gene expression and miRNAs profiling: function and regulation in human epidermal growth factor receptor 2 (HER2)-positive breast cancer
RM Sareyeldin, I Gupta, I Al-Hashimi, HA Al-Thawadi… - Cancers, 2019 - mdpi.com
Breast cancer is the second most common cause of cancer-related deaths among women
worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the …
worldwide. It is a heterogeneous disease with four major molecular subtypes. One of the …
[HTML][HTML] Tumour profiling tests to guide adjuvant chemotherapy decisions in early breast cancer: a systematic review and economic analysis.
S Harnan, P Tappenden, K Cooper… - Health Technology …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Breast cancer and its treatment can have an impact on health-related
quality of life and survival. Tumour profiling tests aim to identify whether or not women need …
quality of life and survival. Tumour profiling tests aim to identify whether or not women need …
Real world data analysis of next generation sequencing and protein expression in metastatic breast cancer patients
D Hempel, F Ebner, A Garg, Z Trepotec, A Both… - Scientific reports, 2020 - nature.com
Next generation sequencing (NGS) together with protein expression analysis is back bone
of molecularly targeted therapy in precision medicine. Our retrospective study shows our …
of molecularly targeted therapy in precision medicine. Our retrospective study shows our …
[HTML][HTML] Dissecting the biology of menstrual cycle-associated breast cancer risk
Fluctuations in circulating estrogen and progesterone across the menstrual cycle lead to
increased breast cancer susceptibility in women; however, the biological basis for this …
increased breast cancer susceptibility in women; however, the biological basis for this …
Secreted breast tumor interstitial fluid microRNAs and their target genes are associated with triple-negative breast cancer, tumor grade, and immune infiltration
Background Studies on tumor-secreted microRNAs point to a functional role of these in
cellular communication and reprogramming of the tumor microenvironment. Uptake of tumor …
cellular communication and reprogramming of the tumor microenvironment. Uptake of tumor …
L0-sparse canonical correlation analysis
Canonical Correlation Analysis (CCA) models are powerful for studying the associations
between two sets of variables. The canonically correlated representations, termed\textit …
between two sets of variables. The canonically correlated representations, termed\textit …
Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes
Young women's breast cancer (YWBC) has poor prognosis and known interactions with
parity. Women diagnosed within 5–10 years of childbirth, defined as postpartum breast …
parity. Women diagnosed within 5–10 years of childbirth, defined as postpartum breast …
Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects
T Osako, H Lee, G Turashvili, D Chiu, S McKinney… - Nature Cancer, 2020 - nature.com
The magnitude and scope of intrinsic age-correlated and host endocrine age-correlated
gene expression in breast cancer is not well understood. From age-correlated gene …
gene expression in breast cancer is not well understood. From age-correlated gene …