The blood–brain barrier (BBB) is a dynamic platform for exchange of substances between
the blood and the brain parenchyma, and it is an essential functional gatekeeper for the …

This review summarises the literature on shift work and its relation to insufficient sleep,
chronic diseases, and accidents. It is based on 38 meta-analyses and 24 systematic …

OSA is a chronic treatable sleep disorder and a frequent comorbidity in patients with type 2
diabetes. Cardinal features of OSA, including intermittent hypoxemia and sleep …

Abstract Circadian (∼ 24-hour) timing systems pervade all kingdoms of life and temporally
optimize behavior and physiology in humans. Relatively recent changes to our …

Bariatric surgery is today the most effective long-term therapy for the management of
patients with severe obesity, and its use is recommended by the relevant guidelines of the …

Sleep disorders are linked to development of type 2 diabetes and increase the risk of
developing diabetes complications. Treating sleep disorders might therefore play an …

Summary Sleep disturbances [short (< 6 h) and long (> 8 h) sleeping time, insomnia
(initiating or maintaining sleep), obstructive sleep apnea (OSA) and abnormal sleep timing] …

Although all types of diabetes result in hyperglycemia, the pathophysiology of each type of
diabetes is different. These guidelines summarize available data specific to the …

Depression is twice as common in people with type 1 or type 2 diabetes as in the general
population, and is associated with poor outcomes. Evidence is growing that depression and …

Background: Obesity is one of the leading causes of preventable death worldwide.
Circadian rhythms are known to control both sleep timing and energy homeostasis, and …